Control of satellite cell function in muscle regeneration and its disruption in ageing

P Sousa-Victor, L García-Prat… - … Reviews Molecular Cell …, 2022 - nature.com
Skeletal muscle contains a designated population of adult stem cells, called satellite cells,
which are generally quiescent. In homeostasis, satellite cells proliferate only sporadically …

Inflammation in duchenne muscular dystrophy–exploring the role of neutrophils in muscle damage and regeneration

A Tulangekar, TE Sztal - Biomedicines, 2021 - mdpi.com
Duchenne muscular dystrophy (DMD) is a severe and progressive, X-linked, neuromuscular
disorder caused by mutations in the dystrophin gene. In DMD, the lack of functional …

Histological methods to assess skeletal muscle degeneration and regeneration in Duchenne muscular dystrophy

N Dubuisson, R Versele, C Planchon… - International journal of …, 2022 - mdpi.com
Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of
function of the protein dystrophin. This protein contributes to the stabilisation of striated cells …

Loss of full-length dystrophin expression results in major cell-autonomous abnormalities in proliferating myoblasts

MRF Gosselin, V Mournetas, M Borczyk, S Verma… - Elife, 2022 - elifesciences.org
Duchenne muscular dystrophy (DMD) affects myofibers and muscle stem cells, causing
progressive muscle degeneration and repair defects. It was unknown whether dystrophic …

[HTML][HTML] The therapeutic relevance of urolithins, intestinal metabolites of ellagitannin-rich food: A systematic review of in vivo studies

WK Tow, PY Chee, U Sundralingam, UD Palanisamy - Nutrients, 2022 - mdpi.com
Nutrients | Free Full-Text | The Therapeutic Relevance of Urolithins, Intestinal Metabolites of
Ellagitannin-Rich Food: A Systematic Review of In Vivo Studies Next Article in Journal Sex …

Gpr18 agonist dampens inflammation, enhances myogenesis, and restores muscle function in models of Duchenne muscular dystrophy

J Dort, Z Orfi, M Fiscaletti, PM Campeau… - Frontiers in Cell and …, 2023 - frontiersin.org
Introduction: Muscle wasting in Duchenne Muscular Dystrophy is caused by myofiber
fragility and poor regeneration that lead to chronic inflammation and muscle replacement by …

RhoA/ROCK signalling activated by ARHGEF3 promotes muscle weakness via autophagy in dystrophic mdx mice

JS You, Y Kim, S Lee, R Bashir… - Journal of Cachexia …, 2023 - Wiley Online Library
Background Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, leads
to progressive and fatal muscle weakness through yet‐to‐be‐fully deciphered molecular …

Cultured myoblasts derived from rat soleus muscle show altered regulation of proliferation and myogenesis during the course of mechanical unloading

MY Komarova, SV Rozhkov, OA Ivanova… - International Journal of …, 2022 - mdpi.com
The structure and function of soleus muscle fibers undergo substantial remodeling under
real or simulated microgravity conditions. However, unloading-induced changes in the …

Interplay between Pitx2 and Pax7 temporally governs specification of extraocular muscle stem cells

M Kuriki, A Korb, G Comai, S Tajbakhsh - PLoS genetics, 2024 - journals.plos.org
Gene regulatory networks that act upstream of skeletal muscle fate determinants are distinct
in different anatomical locations. Despite recent efforts, a clear understanding of the cascade …

[HTML][HTML] Cellular pathogenesis of Duchenne muscular dystrophy: progressive myofibre degeneration, chronic inflammation, reactive myofibrosis and satellite cell …

P Dowling, D Swandulla… - European Journal of …, 2023 - ncbi.nlm.nih.gov
Duchenne muscular dystrophy is a highly progressive muscle wasting disease of early
childhood and characterized by complex pathophysiological and histopathological changes …