[HTML][HTML] CYP2D6 overview: allele and phenotype frequencies
M Kane - Medical Genetics Summaries [Internet], 2021 - ncbi.nlm.nih.gov
Genetic variation has a significant impact on an individual's metabolism and response to a
wide range of medications. The cytochrome P450 family of enzymes are key determinants in …
wide range of medications. The cytochrome P450 family of enzymes are key determinants in …
[HTML][HTML] Bedside testing of CYP2C19 vs. conventional clopidogrel treatment to guide antiplatelet therapy in ST-segment elevation myocardial infarction patients
Background ST-segment elevation myocardial infarction (STEMI) patients are treated with
dual antiplatelet therapy comprising aspirin and a P2Y 12 inhibitor. Clopidogrel is widely …
dual antiplatelet therapy comprising aspirin and a P2Y 12 inhibitor. Clopidogrel is widely …
Genetic variations and epigenetic modulations in CYP genes: Implications in NSAID-treatment of arthritis patients
SR Chowdhury, OD Gupta, AK Ghosh, PS Singha… - The Nucleus, 2021 - Springer
Drugs show specific pharmacodynamic properties and a plethora of adverse drug reactions
depending on the genetic makeup of their users. Pharmacogenomics explains the variations …
depending on the genetic makeup of their users. Pharmacogenomics explains the variations …
[HTML][HTML] Tacrolimus-induced neurotoxicity in early post-liver transplant Saudi patients: incidence and risk factors
DA Alissa, D Alkortas, M Alsebayel… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Tacrolimus is a calcineurin inhibitor (CNI) commonly used as an
immunosuppressant to prevent the rejection of organ transplants. After liver transplantation …
immunosuppressant to prevent the rejection of organ transplants. After liver transplantation …