GABAA receptor modulators are structurally almost as diverse as their target protein. A
plethora of heterocyclic scaffolds has been described as modulating this extremely important …

Background S100A12 is related to acute brain injury and inflammation. We investigated the
clinical prognostic value of serum S100A12 in patients with severe traumatic brain injury …

The aim of this study was to investigate the therapeutic effect of growth differentiation factor 5
(GDF-5) on traumatic brain injury (TBI) in mice. We utilized a controlled cortical impact to …

Predicting the functional recovery of patients with severe neurological condition due to
coronavirus disease 2019 (COVID-19) is a challenging task. Only limited outcome data are …

Neuronal apoptosis is mediated by intrinsic and extrinsic signaling pathways such as the
membrane-mediated, mitochondrial, and endoplasmic reticulum stress pathways. Few …

Background Galectin-3 plays a significant role in microglia activation. Its increased
circulating concentration has been associated with some inflammatory diseases. In-hospital …

The present study examined the effects of dexmedetomidine (Dex) on cognitive and motor
recovery in mice following traumatic brain injury (TBI). TBI induces synaptic damage, which …

Background Cerebral hemodynamic transformation is a relatively common finding in
patients with traumatic brain injury (TBI). Knowledge of cerebral hemodynamic disturbance …

Background Patients with severe acute brain injury have a high risk of a poor clinical
outcome due to primary and secondary brain injury. Ketamine reportedly inhibits cortical …

Background There have yet to be any large-scale studies in China on headaches after
traumatic brain injury (TBI). We evaluate the incidence of headache after TBI and investigate …