[HTML][HTML] Development, recent advances, and updates in binary, ternary co-amorphous systems, and ternary solid dispersions

A Saberi, M Kouhjani, D Yari, A Jahani… - Journal of Drug Delivery …, 2023 - Elsevier
Binary co-amorphous systems (CAMS) are a type of solid dispersion containing an active
pharmaceutical ingredient (API) and small molecule excipients. The properties of these …

Innovations in thermal processing: hot-melt extrusion and KinetiSol® dispersing

DK Tan, DA Davis Jr, DA Miller, RO Williams III… - Aaps Pharmscitech, 2020 - Springer
Thermal processing has gained much interest in the pharmaceutical industry, particularly for
the enhancement of solubility, bioavailability, and dissolution of active pharmaceutical …

Solid-liquid equilibrium behavior and thermodynamic analysis of dipyridamole in pure and binary solvents from 293.15 K to 328.15 K

S Wang, Y Chen, T Gong, W Dong, G Wang, H Li… - Journal of Molecular …, 2019 - Elsevier
The solubility of dipyridamole was determined in five pure solvents (methanol, ethanol, 1-
propanol, 2-propanol and 1-butanol) and three binary solvents (methanol+ water, ethanol+ …

[HTML][HTML] Enhanced pharmacokinetic performance of dapoxetine hydrochloride via the formulation of instantly-dissolving buccal films with acidic pH modifier and …

HM Aldawsari, SM Badr-Eldin - Journal of Advanced Research, 2020 - Elsevier
Instantly dissolving buccal films have gained attention owing to their easy administration and
capability to surmount the hepatic first pass effect of drugs. Dapoxetine hydrochloride (DPX) …

Enhancement of solubility and dissolution rate of dipyridamole by salifying: Preparation, characterization, and theoretical calculation

D Yi, Y Dong, Y Yao, M Hong, B Zhu, GB Ren… - Journal of Molecular …, 2024 - Elsevier
Dipyridamole (DIP) is a medication utilized to treat cardiovascular diseases, belonging to the
BCS II class of drugs with low solubility and high permeability. As the effectiveness of oral …

Melting point depression for enhanced dissolution rate of eslicarbazepine acetate

EM Dorgham, GM El Maghraby, EA Essa… - Drug Development …, 2023 - Taylor & Francis
Background Eslicarbazepine acetate (ESL) is antiepileptic agent which is approved for use
as single therapy or in combination with other drugs. However, it suffers from poor oral …

Improvement of physicochemical and solubility of dipyridamole by cocrystallization technology

A Gawade, A Kuchekar, S Boldhane… - Journal of Drug Delivery …, 2021 - jddtonline.info
The aim of this study was to develop a pH-independent release formulation of dipyridamole
(DP) by the combined use of pH-modifier technology and cocrystal technology tartaric acid …

In vivo evaluation for the anticoagulant activity of dipyridamole matrix tablets

A Gawade, S Boldhane, A Pawar… - Research Journal of …, 2023 - indianjournals.com
Dipyridamole (DYP) is potent drug that prevents the thromboembolic risk. It has been
clinically used for chronic treatment of angina pectoris treatment and during the valve …

Dipyridamole cocrystal tablets with enhanced solubility and dissolution at intestinal pH

M Nijhawan, S Dhyagala, S Gunnam… - Fabad Journal of …, 2024 - dergipark.org.tr
The aim of the study was to prepare dipyridamole (DPM) cocrystals to alter
itsphysicochemical properties as it ispoorly soluble in water, 6.8 pHbuffer and belongs to …

Development and Evaluation of dipyridamole matrix tablets using response surface methodology

AR Gawade, SP Boldhane - Research Journal of Pharmacy and …, 2021 - indianjournals.com
The sustained release matrix dosage type is favored to prevent blood level variations found
in the Dipyridamole drug. The goal of this research was to formulate Dipyridamole's …