The potential of the mucoadhesive film technology is hard to ignore, owing to perceived
superior patient acceptability versus buccal tablets, and significant therapeutic opportunities …

Oral administration is preferred over other drug delivery methods due to its safety, high
patient compliance, ease of ingestion without discomfort, and tolerance of a wide range of …

Controlled oral delivery of bioactive molecules remains a promising platform for the food and
biomedical realm. Nonetheless, there are many bottlenecks to the efficient oral bioactive …

Soft robotics could help providing a better understanding of the mechanisms underpinning
the swallowability of solid oral dosage forms (SODF), especially by vulnerable populations …

Long-acting antiretroviral products have the potential to transform human immunodeficiency
virus (HIV) prevention and treatment approaches in pediatric populations. Broadly …

Current therapeutic drugs for ulcerative colitis (UC) remained inadequate due to drug
dependence and unacceptable adverse events. Reactive oxygen species (ROS) played a …

This study investigated the impact of gastro-intestinal fluid volume and bile salt (BS)
concentration on the dissolution of carbamazepine (CBZ) immediate release (IR) 100 mg …

The paradigm of pediatric drug development has been evolving in a “carrot-and-stick”-based
tactic to address population-specific issues. However, the off-label prescription of adult …

In infants, gastric digestion is a crucial step for the digestion and absorption of nutrients from
infant formula, human milk, or any other milk substitutes. Critical understanding of the …

The present study aimed to explore the usefulness of beagle dogs in combination with
physiologically based pharmacokinetic (PBPK) modeling in the evaluation of drug exposure …