2023 ESC Guidelines for the management of cardiomyopathies: Developed by the task force on the management of cardiomyopathies of the European Society of …

E Arbelo, A Protonotarios, JR Gimeno… - European heart …, 2023 - academic.oup.com
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Excessive Trabeculation of the Left Ventricle: JACC: Cardiovascular Imaging Expert Panel Paper

SE Petersen, B Jensen, N Aung, MG Friedrich… - Cardiovascular …, 2023 - jacc.org
Excessive trabeculation, often referred to as “noncompacted” myocardium, has been
described at all ages, from the fetus to the adult. Current evidence for myocardial …

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic …

AR Lyon, T López-Fernández, LS Couch… - European Heart …, 2022 - academic.oup.com
ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

Cardiac sarcoidosis: phenotypes, diagnosis, treatment, and prognosis

J Lehtonen, V Uusitalo, P Pöyhönen… - European Heart …, 2023 - academic.oup.com
Cardiac sarcoidosis (CS) results from epithelioid cell granulomas infiltrating the myocardium
and predisposing to conduction disturbances, ventricular tachyarrhythmias, and heart …

Spotlight on the 2022 ESC guideline management of ventricular arrhythmias and prevention of sudden cardiac death: 10 novel key aspects

H Könemann, N Dagres, JL Merino, C Sticherling… - Europace, 2023 - academic.oup.com
Sudden cardiac death and ventricular arrhythmias are a global health issue. Recently, a
new guideline for the management of ventricular arrhythmias and prevention of sudden …

The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action

E Marijon, K Narayanan, K Smith, S Barra, C Basso… - The Lancet, 2023 - thelancet.com
Despite major advancements in cardiovascular medicine, sudden cardiac death (SCD)
continues to be an enormous medical and societal challenge, claiming millions of lives …

AIEgen‐Based Covalent Organic Frameworks for Preventing Malignant Ventricular Arrhythmias Via Local Hyperthermia Therapy

L Zhang, F Guo, S Xu, Q Deng, M Xie, J Sun… - Advanced …, 2023 - Wiley Online Library
The engineering of aggregation‐induced emission luminogens (AIEgen) based covalent
organic frameworks (COFs), TDTA‐COF, BTDTA‐COF, and BTDBETA‐COF are reported, as …

Dilated cardiomyopathy: causes, mechanisms, and current and future treatment approaches

S Heymans, NK Lakdawala, C Tschöpe, K Klingel - The Lancet, 2023 - thelancet.com
Dilated cardiomyopathy is conventionally defined as the presence of left ventricular or
biventricular dilatation or systolic dysfunction in the absence of abnormal loading conditions …

Myocardial inflammation as a manifestation of genetic cardiomyopathies: from bedside to the bench

G Peretto, E Sommariva, C Di Resta, M Rabino… - Biomolecules, 2023 - mdpi.com
Over recent years, preclinical and clinical evidence has implicated myocardial inflammation
(M-Infl) in the pathophysiology and phenotypes of traditionally genetic cardiomyopathies. M …

Mislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3

J Kornienko, M Rodríguez-Martínez, K Fenzl… - Nature …, 2023 - nature.com
Severe forms of dilated cardiomyopathy (DCM) are associated with point mutations in the
alternative splicing regulator RBM20 that are frequently located in the arginine/serine-rich …