Despite expressing many key risk genes, the role of microglia in late-onset Alzheimer's
disease pathophysiology is somewhat ambiguous, with various phenotypes reported to be …

The interaction between the peripheral immune system and the brain is increasingly being
recognized as an important layer of neuroimmune regulation and plays vital roles in brain …

Cerebral (Aβ) plaque and (pTau) tangle deposition are hallmarks of Alzheimer's disease
(AD), yet are insufficient to confer complete AD-like neurodegeneration experimentally …

Abstract Background Inflammatory Bowel Diseases (IBD), an autoimmune disease
characterised by abnormal intestinal immunity, are related to vital morbidity around the …

Natural killer (NK) cells and cytotoxic T (CD8+) cells are two of the most important types of
immune cells in our body, protecting it from deadly invaders. While the NK cell is part of the …

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder with pathological
features of β-amyloid (Aβ) and hyperphosphorylated tau protein accumulation in the brain …

The development of seizures in epilepsy syndromes associated with malformations of
cortical development (MCDs) has traditionally been attributed to intrinsic cortical alterations …

The etiology of various neurodegenerative disorders that mainly affect the central nervous
system including (but not limited to) Alzheimer's disease, Parkinson's disease and …

Flaviviruses are a family of enveloped viruses with a positive-sense RNA genome,
transmitted by arthropod vectors. These viruses are known for their broad cellular tropism …

Background Alzheimer's disease (AD) is the most frequent cause of dementia. Recent
evidence suggests the involvement of peripheral immune cells in the disease, but the …