Tire-rubber related pollutant 6-PPD quinone: A review of its transformation, environmental distribution, bioavailability, and toxicity

X Hua, D Wang - Journal of hazardous materials, 2023 - Elsevier
The antioxidant 6-PPD has been widely used to prevent cracking and thermal oxidative
degradation and to extend the service life of tire rubber. 6-PPD quinone (6-PPDQ) is formed …

A mini review on 6PPD quinone: A new threat to aquaculture and fisheries

K Bohara, A Timilsina, K Adhikari, A Kafle… - Environmental …, 2023 - Elsevier
Numerous toxic substances are directly and indirectly discharged by humans into water
bodies, causing distress to the organisms living on it. 6PPD, an amino antioxidant from tires …

Environmental occurrence and toxicity of 6PPD quinone, an emerging tire rubber-derived chemical: a review

K Zoroufchi Benis, A Behnami, S Minaei… - … & Technology Letters, 2023 - ACS Publications
N-(1, 3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is a chemical added to tires
to prevent their oxidative degradation. 6PPD is highly reactive with ozone and oxygen …

Exposure to 6-PPD Quinone at Environmentally Relevant Concentrations Inhibits Both Lifespan and Healthspan in C. elegans

X Hua, D Wang - Environmental Science & Technology, 2023 - ACS Publications
N-(1, 3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine (6-PPD), one of the most common
additives used in rubber, enters the environment due to significant emissions of tire wear …

Four-week repeated exposure to tire-derived 6-PPD quinone causes multiple organ injury in male BALB/c mice

W He, A Gu, D Wang - Science of the Total Environment, 2023 - Elsevier
Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6-PPDQ) is the
ozonation product of tire antioxidant 6-PPD. 6-PPDQ can be detected in different …

Occurrence of p-phenylenediamine antioxidants (PPDs) and PPDs-derived quinones in indoor dust

J Zhu, R Guo, S Jiang, P Wu, H Jin - Science of The Total Environment, 2024 - Elsevier
The p-phenylenediamine antioxidants (PPDs) have been widely detected in various dust
samples. Nevertheless, the knowledge on occurrence of their environmental transformation …

Exposure to 6-PPD quinone enhances lipid accumulation through activating metabolic sensors of SBP-1 and MDT-15 in Caenorhabditis elegans

Y Wang, X Hua, D Wang - Environmental Pollution, 2023 - Elsevier
Although it has been shown that exposure to 6-PPDQ can cause toxicity on environmental
organisms, its possible effects on metabolic state remain largely unclear. We here …

Characterization of N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD)-induced cardiotoxicity in larval zebrafish (Danio rerio)

C Fang, L Fang, S Di, Y Yu, X Wang, C Wang… - Science of The Total …, 2023 - Elsevier
Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is a type of p-
phenylenediamine (PPD), which is widely used in the manufacture of rubber tires owing to …

Occurrence of p-phenylenediamine antioxidants in human urine

W Mao, H Jin, R Guo, P Chen, S Zhong, X Wu - Science of The Total …, 2024 - Elsevier
General populations are widely exposed to various p-phenylenediamine antioxidants
(PPDs). N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD), a typical p …

Polyethylene nanoparticles at environmentally relevant concentrations enhances neurotoxicity and accumulation of 6-PPD quinone in Caenorhabditis elegans

X Hua, D Wang - Science of The Total Environment, 2024 - Elsevier
The exposure risk of 6-PPD quinone (6-PPDQ) has aroused increasing concern. In the
natural environment, 6-PPDQ could interact with other pollutants, posing more severe …