[HTML][HTML] Progesterone actions and resistance in gynecological disorders

JA MacLean, K Hayashi - Cells, 2022 - mdpi.com
Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

[HTML][HTML] Efficacy of therapies and interventions for repeated embryo implantation failure: a systematic review and meta-analysis

A Busnelli, E Somigliana, F Cirillo, A Baggiani… - Scientific Reports, 2021 - nature.com
The aim of the present systematic review and meta-analysis was to assess the effect of the
different therapeutic options for repeated embryo implantation failure (RIF) on a subsequent …

Primary specification of blastocyst trophectoderm by scRNA-seq: New insights into embryo implantation

D Liu, Y Chen, Y Ren, P Yuan, N Wang, Q Liu… - Science …, 2022 - science.org
Mechanisms of implantation such as determination of the attachment pole, fetal-maternal
communication, and underlying causes of implantation failure are largely unexplored. Here …

Human implantation: The complex interplay between endometrial receptivity, inflammation, and the microbiome

J Sehring, A Beltsos, R Jeelani - Placenta, 2022 - Elsevier
Human embryo implantation is an intricate spatiotemporal process that involves the intimate
association between the embryo and the endometrium of the mother. During implantation …

[HTML][HTML] Single-cell transcriptome profiling of the human endometrium of patients with recurrent implantation failure

ZZ Lai, Y Wang, WJ Zhou, Z Liang, JW Shi, HL Yang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Introduction: Despite great advances in assisted reproductive technology (ART), recurrent
implantation failure (RIF) cannot be effectively avoided. Notably, cellular characteristics and …

[HTML][HTML] Review of endometrial receptivity array: a personalized approach to embryo transfer and its clinical applications

SC Rubin, M Abdulkadir, J Lewis… - Journal of Personalized …, 2023 - mdpi.com
Successful outcomes of in vitro fertilization (IVF) rely on both the formation of a
chromosomally normal embryo and its implantation in a receptive endometrium. Pre …

Clinical consequences of defective decidualization

C Ticconi, N Di Simone, L Campagnolo, A Fazleabas - Tissue and Cell, 2021 - Elsevier
Decidualization is characterized by a series of genetic, metabolic, morphological,
biochemical, vascular and immune changes occurring in the endometrial stroma in …

[HTML][HTML] Increased METTL3-mediated m6A methylation inhibits embryo implantation by repressing HOXA10 expression in recurrent implantation failure

P Xue, W Zhou, W Fan, J Jiang, C Kong… - Reproductive Biology …, 2021 - Springer
Background Recurrent implantation failure (RIF) is a major limitation of assisted reproductive
technology, which is associated with impaired endometrial receptivity. Although N 6 …

An algorithm to personalise the diagnosis of recurrent implantation failure based on theoretical cumulative implantation rate

G Rozen, P Rogers, WT Teh, CJ Stern… - Human …, 2021 - academic.oup.com
Recurrent implantation failure (RIF) is an imprecisely defined disorder lacking a robust
scientific basis. The incomplete understanding of RIF provides significant diagnostic and …

[HTML][HTML] TOP2A deficit-induced abnormal decidualization leads to recurrent implantation failure via the NF-κB signaling pathway

H Fu, W Tan, Z Chen, Z Ye, Y Duan, J Huang… - Reproductive Biology …, 2022 - Springer
Background Successful implantation is a complex process that is influenced by embryo
quality, endometrial receptivity, immune factors, and the specific type of in vitro fertilization …