[HTML][HTML] Safety of MET tyrosine kinase inhibitors in patients with MET exon 14 skipping non-small cell lung cancer: a clinical review

A Cortot, X Le, E Smit, S Viteri, T Kato, H Sakai… - Clinical lung cancer, 2022 - Elsevier
Abstract Introduction MET exon 14 (METex14) skipping mutations occur in 3–4% of non-
small-cell lung cancer (NSCLC) cases. Currently, four oral MET tyrosine kinase inhibitors …

[HTML][HTML] A Cross-Talk about Radioresistance in Lung Cancer—How to Improve Radiosensitivity According to Chinese Medicine and Medicaments That Commonly …

P Nowak, I Bil-Lula, M Śliwińska-Mossoń - International Journal of …, 2023 - mdpi.com
Lung cancer is one of the most common cancers in the population and is characterized by
non-specific symptoms that delay the diagnosis and reduce the effectiveness of oncological …

[PDF][PDF] NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis

D Sengupta, L Zeng, Y Li, S Hausmann, D Ghosh… - Molecular cell, 2021 - cell.com
The etiological role of NSD2 enzymatic activity in solid tumors is unclear. Here we show that
NSD2, via H3K36me2 catalysis, cooperates with oncogenic KRAS signaling to drive lung …

Pulmonary delivery of osimertinib liposomes for non-small cell lung cancer treatment: formulation development and in vitro evaluation

SS Sawant, SM Patil, SK Shukla, NS Kulkarni… - Drug Delivery and …, 2022 - Springer
Osimertinib (OB) is a third-generation irreversible tyrosine kinase inhibitor targeting the
epidermal growth factor receptor (EGFR), overexpressed in non-small cell lung cancer …

Top advances of the year: Precision oncology

A Desai, NK Reddy, V Subbiah - Cancer, 2023 - Wiley Online Library
The advent of precision medicine has changed the landscape of oncologic biomarkers, drug
discovery, drug development, and, more importantly, outcomes for patients with cancer …

[HTML][HTML] A retrospective study of postoperative targeted therapy in ALK-positive lung cancer

B Wang, Y Song, Z Chen, X Su, X Yang, Z Wei… - Scientific Reports, 2023 - nature.com
In this study, we aim to investigate the therapeutic effect and safety of ALK inhibitor in ALK-
positive lung cancer patients. 59 patients with ALK-positive lung cancer from August 2013 to …

[HTML][HTML] Activities against lung cancer of biosynthesized silver nanoparticles: a review

JL Mejía-Méndez, ER López-Mena, E Sánchez-Arreola - Biomedicines, 2023 - mdpi.com
Nanomedicine is an interdisciplinary field where nanostructured objects are applied to treat
or diagnose disease. Nanoparticles (NPs) are a special class of materials at nanometric …

[HTML][HTML] Global research landscape and trends of lung cancer immunotherapy: a bibliometric analysis

Y Liu, X Cheng, X Han, X Cheng, S Jiang… - Frontiers in …, 2022 - frontiersin.org
​ Background Immunotherapy for lung cancer has been a hot research area for years. This
bibliometric analysis aims to present the research trends on lung cancer immunotherapy …

[HTML][HTML] Driver genes associated with the incidence of venous thromboembolism in patients with non-small-cell lung cancer: a systematic review and meta-analysis

X Qian, M Fu, J Zheng, J Zhou, J Zhou - Frontiers in Oncology, 2021 - frontiersin.org
Background The association between driver genes and the incidence of thromboembolic
events (TEs) in patients diagnosed with non-small-cell lung cancer (NSCLC) needs to be …

Impact of tumor suppressor gene co-mutations on differential response to EGFR TKI therapy in EGFR L858R and Exon 19 deletion lung cancer

JA Hellyer, MN White, RM Gardner, K Cunanan… - Clinical Lung Cancer, 2022 - Elsevier
Background In most studies, patients with EGFR L858R mutant non-small cell lung cancer
(NSCLC) have a shorter duration of response to EGFR tyrosine kinase inhibitor (TKI) therapy …