Targeted EGFR Nanotherapy in Non-Small Cell Lung Cancer

A Crintea, AM Constantin, AC Motofelea… - Journal of Functional …, 2023 - mdpi.com
Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality
worldwide. Despite advances in treatment, the prognosis remains poor, highlighting the …

Recommendations for reporting tissue and circulating tumour (ct) DNA next-generation sequencing results in non-small cell lung cancer

U Malapelle, N Leighl, A Addeo, D Hershkovitz… - British Journal of …, 2024 - nature.com
Non-small cell lung cancer is a heterogeneous disease and molecular characterisation
plays an important role in its clinical management. Next-generation sequencing-based …

[HTML][HTML] Multiplexed electrokinetic sensor for detection and therapy monitoring of extracellular vesicles from liquid biopsies of non-small-cell lung cancer patients

S Cavallaro, P Hååg, SS Sahu, L Berisha… - Biosensors and …, 2021 - Elsevier
Liquid biopsies based on extracellular vesicles (EVs) represent a promising tool for
treatment monitoring of tumors, including non-small-cell lung cancers (NSCLC). In this study …

Prevalence of oncogenic driver mutations in Hispanics/Latin patients with lung cancer. A systematic review and meta-analysis

R Parra-Medina, JP Castañeda-González, L Montoya… - Lung Cancer, 2023 - Elsevier
Introduction The frequency of actionable mutations varies between races, and
Hispanic/Latino (H/L) people are a population with different proportions of ancestry. Our …

Efficacy of PP121 in primary and metastatic non‑small cell lung cancers

QA Quick - Biomedical Reports, 2023 - spandidos-publications.com
Tyrosine kinase inhibitors are a clinically standard treatment option for non‑small cell lung
cancers (NSCLCs), the leading cause of cancer‑related deaths in the US. These targeted …

High expression of NT5DC2 is a negative prognostic marker in pulmonary adenocarcinoma

AB Schulze, A Kuntze, LH Schmidt, M Mohr, A Marra… - Cancers, 2022 - mdpi.com
Simple Summary Lung cancer is the leading cause of cancer related deaths and non-small
cell lung cancer (NSCLC) is its most relevant subtype. Here, we present data on p53 co …

Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin

CA Allred, C Gormley, I Venugopal, S Li… - Communications …, 2023 - nature.com
There continues to be a need for cancer-specific ligands that can deliver a wide variety of
therapeutic cargos. Ligands demonstrating both tumor-specificity and the ability to mediate …

Primary Lung Cancer Organoids for Personalized Medicine—Are They Ready for Clinical Use?

RS Werner, MB Kirschner, I Opitz - Cancers, 2021 - mdpi.com
Simple Summary Identification of novel therapeutic strategies for the treatment of non-small
cell lung cancer (NSCLC) remains an urgent need in the area of lung cancer research …

Oncogenic fusions in gliomas: An institutional experience

J Polivka, M Svajdler, V Priban, J Mracek… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: Gliomas are primary malignancies of the central nervous system (CNS).
High-grade gliomas are associated with poor prognosis and modest survival rates despite …

[HTML][HTML] Therapeutic strategy using novel RET/YES1 dual-target inhibitor in lung cancer

YJ Choi, M Choi, J Park, M Park, MJ Kim, J Lee… - Biomedicine & …, 2024 - Elsevier
Lung cancer represents a significant global health concern and stands as the leading cause
of cancer-related mortality worldwide. The identification of specific genomic alterations such …