International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Diagnostics and management of male infertility in primary ciliary dyskinesia

CN Jayasena, A Sironen - Diagnostics, 2021 - mdpi.com
Primary ciliary dyskinesia (PCD), a disease caused by the malfunction of motile cilia,
manifests mainly with chronic recurrent respiratory infections. In men, PCD is also often …

Inherently disordered regions of axonemal dynein assembly factors

SM King - Cytoskeleton, 2023 - Wiley Online Library
The dynein‐driven beating of cilia is required to move individual cells and to generate fluid
flow across surfaces and within cavities. These motor enzymes are highly complex and can …

Dyslexia‐Related Hearing Loss Occurs Mainly through the Abnormal Spontaneous Electrical Activity of Spiral Ganglion Neurons

G Hong, X Fu, X Chen, L Zhang, X Han… - Advanced …, 2023 - Wiley Online Library
Dyslexia is a reading and spelling disorder due to neurodevelopmental abnormalities and is
occasionally found to be accompanied by hearing loss, but the reason for the associated …

Methylation of ciliary dynein motors involves the essential cytosolic assembly factor DNAAF3/PF22

M Sakato-Antoku, RS Patel-King… - Proceedings of the …, 2024 - National Acad Sciences
Axonemal dynein motors drive ciliary motility and can consist of up to twenty distinct
components with a combined mass of~ 2 MDa. In mammals, failure of dyneins to assemble …

Impact of primary ciliary dyskinesia: Beyond sinobronchial syndrome in Japan

N Keicho, M Hijikata, A Miyabayashi… - Respiratory …, 2024 - Elsevier
Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterized by impaired motile
cilia function, particularly in the upper and lower airways. To date, more than 50 causative …

Restoring Ciliary Function: Gene Therapeutics for Primary Ciliary Dyskinesia

NW Keiser, E Cant, S Sitaraman, A Shoemark… - Human gene …, 2023 - liebertpub.com
Primary ciliary dyskinesia (PCD) is a genetic disease characterized by defects in motile cilia,
which play an important role in several organ systems. Lung disease is a hallmark of PCD …

Respiratory Aspects of Primary Ciliary Dyskinesia

W De Jesús-Rojas, AJ Shapiro… - Clinics in Chest …, 2024 - chestmed.theclinics.com
Primary ciliary dyskinesia (PCD) is a rare genetic disorder affecting motile cilia in the
respiratory tract. 1 The estimated prevalence is 1: 7500 to 1: 15,000, although recent studies …

Primary ciliary dyskinesia and bronchiectasis: new data and future challenges

CO Pioch, DW Connell… - Archivos de …, 2023 - pubmed.ncbi.nlm.nih.gov
Primary Ciliary Dyskinesia and Bronchiectasis: New Data and Future Challenges Primary
Ciliary Dyskinesia and Bronchiectasis: New Data and Future Challenges Arch …

CFAP300 mutation causing primary ciliary dyskinesia in Finland

R Schultz, V Elenius, MR Fassad, G Freke… - Frontiers in …, 2022 - frontiersin.org
Primary ciliary dyskinesia (PCD) is a rare genetic condition characterized by chronic
respiratory tract infections and in some cases laterality defects and infertility. The symptoms …