A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Background Our recent meta-analysis indicated that vitamin C may shorten the length of ICU
stay and the duration of mechanical ventilation. Here we analyze modification of the vitamin …

A number of controlled trials have previously found that in some contexts, vitamin C can
have beneficial effects on blood pressure, infections, bronchoconstriction, atrial fibrillation …

Acute kidney injury (AKI) is a common and severe complication after cardiac surgery.
Currently, a series of novel biomarkers have favored the assessment of AKI after cardiac …

Importance Selenium contributes to antioxidative, anti-inflammatory, and immunomodulatory
pathways, which may improve outcomes in patients at high risk of organ dysfunctions after …

Although the concept of nephrotoxicity has been recognized for more than 80 years, interest
in nephrotoxins has intensified dramatically over the past two decades. Much of this …

Introduction The oxidative damage suffered in cardiac surgery is associated with declining
trace elements which lead to the development of multi organ dysfunction (MOD), acute …

Objects: Cardiac surgery is associated with acute kidney injury (AKI). However, the effects of
various pharmacological and nonpharmacological strategies for AKI prevention have not …

Background The effect of N-acetylcysteine (NAC), an antioxidant, on preventing acute
kidney injury (AKI) and major adverse cardiac events (MACE) remains controversial …

Although extended donor criteria grafts bear a higher risk of complications such as graft
dysfunction, the exceeding demand requires to extent the pool of potential donors. The risk …