Management of bleeding and procedures in patients on antiplatelet therapy

D Swan, N Loughran, M Makris, J Thachil - Blood Reviews, 2020 - Elsevier
Antiplatelet medications have long been the mainstay for secondary prevention in
cardiovascular disorders. More recently, with the advent of coronary stents, there has been …

A 2014 update on coagulation management for cardiopulmonary bypass

RH Thiele, J Raphael - Seminars in cardiothoracic and …, 2014 - journals.sagepub.com
Coagulopathy after cardiac surgery with cardiopulmonary bypass is a serious complication
that may result in massive bleeding requiring transfusion of significant amounts of blood …

Aprotinin in cardiac surgery: a review of conventional and novel mechanisms of action

MD McEvoy, ST Reeves, JG Reves… - Anesthesia & …, 2007 - journals.lww.com
Induction of the coagulation and inflammatory cascades can cause multiorgan dysfunction
after cardiopulmonary bypass (CPB). In light of these observations, strategies that can …

Avoiding transfusions in children undergoing cardiac surgery: a meta-analysis of randomized trials of aprotinin

DM Arnold, DA Fergusson, AKC Chan… - Anesthesia & …, 2006 - journals.lww.com
IMPLICATIONS: In this meta-analysis of randomized controlled trials, aprotinin reduced the
proportion of children who received blood transfusions during cardiac surgery. However, the …

Documento «Sevilla» de consenso sobre alternativas a la transfusión de sangre alogénica

I Alberca, MS Asuero, JL Bóveda, N Carpio… - Medicina Clínica, 2006 - Elsevier
El Documento de Consenso sobre Alternativas a la Transfusión de Sangre Alogénica
(ATSA) ha sido elaborado por un panel de expertos pertenecientes a 5 sociedades …

Brain protection in cardiac surgery

K Grogan, J Stearns, CW Hogue - Anesthesiology clinics, 2008 - Elsevier
Brain injury is a major source of patient morbidity after cardiac surgery, and is associated
with prolonged hospitalization, excessive operative mortality, high hospital costs, and …

Antifibrinolytics in cardiac surgical patients receiving aspirin: a systematic review and meta-analysis

DR McIlroy, PS Myles, LE Phillips… - British journal of …, 2009 - academic.oup.com
While conventional practice is to discontinue aspirin prior to elective cardiac surgery there is
evidence that its continuation may be associated with improved perioperative outcomes …

Anesthetic consideration for descending thoracic aortic aneurysm repair

RA Kahn, ME Stone… - … in Cardiothoracic and …, 2007 - journals.sagepub.com
Anesthesia for surgery of the aorta poses some of the most difficult challenges for
anesthesiologists. Major hemodynamic and physiologic stresses and sophisticated …

A benefit-risk review of systemic haemostatic agents: part 1: in major surgery

IS Fraser, RJ Porte, PA Kouides, AS Lukes - Drug safety, 2008 - Springer
Systemic haemostatic agents play an important role in the management of blood loss during
major surgery where significant blood loss is likely and their use has increased in recent …

Bleeding following deep hypothermia and circulatory arrest in children

EB Mossad, S Machado… - … in Cardiothoracic and …, 2007 - journals.sagepub.com
Deep hypothermic circulatory arrest (DHCA) is a technique of extracorporeal circulation
commonly used in children with complex congenital heart defects undergoing surgical …