Background: The objective of this study was to determine the efficacy and safety of
nebulized 3% hypertonic saline solution and salbutamol in the treatment of mild to moderate …

Importance Two previous meta-analyses of nebulized hypertonic saline (HS) on hospital
length of stay (LOS) in acute viral bronchiolitis have suggested benefit. Neither study fully …

In most circumstances, a nasal route for the delivery of pulmonary aerosol medications is
rarely considered; however, in specific instances, this route may be quite useful. Consider …

Importance Acute bronchiolitis is the most frequent lower respiratory tract infection in infants,
yet there are no effective therapies available. Current evidence is unclear about the role of …

BACKGROUND: Research suggests that hypertonic saline (HS) may improve mucous flow
in infants with acute bronchiolitis. Data suggest a trend favoring reduced length of hospital …

The objective of this study was to determine the efficacy and safety of frequently inhaled
nebulized hypertonic saline (HS) in infants with moderate to severe bronchiolitis. One …

Bronchiolitis is a common disorder in young children that often results in hospitalisation.
Except for a possible effect of nebulised hypertonic saline (sodium chloride), no evidence …

Objective To compare the length of hospital stay (primary) and improvement in clinical
severity scores (secondary) among children with bronchiolitis nebulized with 3% hypertonic …

Nebulized hypertonic saline (HS) treatment reduced the length of hospitalization in infants
with acute bronchiolitis in a previous meta-analysis. However, there was no reduction in the …

BACKGROUND AND OBJECTIVES: Bronchiolitis, the most common reason for
hospitalization in children younger than 1 year in the United States, has no proven therapies …