The future of point-of-care nucleic acid amplification diagnostics after COVID-19: time to walk the walk

J García-Bernalt Diego, P Fernández-Soto… - International Journal of …, 2022 - mdpi.com
Since the onset of the COVID-19 pandemic, over 610 million cases have been diagnosed
and it has caused over 6.5 million deaths worldwide. The crisis has forced the scientific …

The Diagnostic Performance of Various Clinical Specimens for the Detection of COVID-19: A Meta-Analysis of RT-PCR Studies

KSA Al-Shaibari, HAL Mousa, MAA Alqumber… - Diagnostics, 2023 - mdpi.com
Background: The diagnostic performance of numerous clinical specimens to diagnose
COVID-19 through RT-PCR techniques is very important, and the test result outcome is still …

[HTML][HTML] Neutrophil-to-lymphocyte ratio and absolute lymphocyte count as early diagnostic tools for corona virus disease 2019

MF Shahid, A Malik, FA Siddiqi, I Fazal, M Hammad… - Cureus, 2022 - ncbi.nlm.nih.gov
Results Out of the 172 subjects included in the study, the mean age was 40.6±10.0 years,
while 51% of individuals were males. Fever was found to be the most prevalent complaint …

Point-of-Care Testing of COVID-19: Current Status, Clinical Impact, and Future Therapeutic Perspectives

A Gangula, B Kim, B Casey, A Hamill… - Point-of-Care Testing of …, 2022 - Springer
The effective management of the coronavirus disease 2019 (COVID-19) pandemic depends
on the bedrock of rapid and accurate testing to enable promptness in quarantining, contact …

Isothermal amplification technology (IAT) for rapid diagnosis of Rickettsioses: Scope, overview, existing evidence and the way forward

R Dixit, N Gopalan, SK Behera - Diagnostic Microbiology and Infectious …, 2023 - Elsevier
Rickettsioses, a category of zoonosis primarily caused by Rickettsia and Orientia, is a huge
public health problem worldwide. Diseases like murine typhus, scrub typhus, Mediterranean …

Performance Evaluation of Developed Bangasure™ Multiplex rRT-PCR Assay for SARS-CoV-2 Detection in Bangladesh: A Blinded Observational Study at Two …

MH Razu, ZB Ahmed, MI Hossain, MFA Rabbi… - Diagnostics, 2022 - mdpi.com
In this study, we evaluated the performance of the in-house developed rRT-PCR assay for
SARS-CoV-2 RNA targeting the envelope (E) and nucleocapsid (N) genes with internal …

Research of childhood tuberculosis in suspected populations by molecular methods: A multicenter study in China

C Li, S Wang, H Yu, J Wang, J Deng… - Frontiers in Cellular …, 2022 - frontiersin.org
The research of childhood tuberculosis is inadequate in china. The cross-priming
amplification (CPA) of specific DNA in clinical samples is increasingly adopted for the …

[PDF][PDF] 低拷贝病毒RNA 捕获及多重实时荧光定量PCR 检测

余佳, 李晓宁, 肖君华, 李凯, 周宇荀 - 现代生物医学进展, 2022 - biomed.cnjournals.com
摘要目的: 为提高COVID-19 检测灵敏度, 减少新冠患者临床假阴性检测结果, 本研究建立了一种
SARS-CoV-2 低拷贝假病毒RNA 捕获方法. 方法: 利用链霉亲和素磁珠, 设计并合成生物素探针 …

Comparison of the performance of two real-time fluorescent quantitative PCR kits for the detection of SARS-CoV-2 nucleic acid: a study based on large real clinical …

Y Wang, X Li, Y Wang, Z Tu, J Xu, J Pan, Q Zhou - Virology Journal, 2022 - Springer
Background The global pandemic of coronavirus disease 2019 (COVID-19) has led to the
development of multiple detection kits by national manufacturers for severe acute respiratory …

A comparison of SARS-cov-2 RNA extraction with the quickgene-810 nucleic acid isolation system compared to the EZ1 advanced DSP virus kit

T Phan, R Stephenson, T Cai… - Access …, 2022 - microbiologyresearch.org
The QuickGene-810 Nucleic Acid Isolation System is a semi-automated extraction platform
which may be used for RNA extraction. New methods were required to support the rapid …