Inflammation and the dimensions of depression: a review

M Majd, EFH Saunders, CG Engeland - Frontiers in neuroendocrinology, 2020 - Elsevier
Patients with depressive disorders show a wide range of clinical manifestations including
cognitive and neurovegetative symptoms. Importantly, these symptoms can differ in terms of …

C-reactive protein as a biomarker for major depressive disorder?

L Orsolini, S Pompili, S Tempia Valenta, V Salvi… - International journal of …, 2022 - mdpi.com
The etiopathogenesis of depression is not entirely understood. Several studies have
investigated the role of inflammation in major depressive disorder. The present work aims to …

Persistent depressive symptoms, HPA-axis hyperactivity, and inflammation: the role of cognitive-affective and somatic symptoms

E Iob, C Kirschbaum, A Steptoe - Molecular psychiatry, 2020 - nature.com
Abstract Hypothalamic-pituitary-adrenal (HPA)-axis hyperactivity and inflammation are
thought to be prominent in the aetiology of depression. Although meta-analyses have …

Interleukin-6 as potential mediator of long-term neuropsychiatric symptoms of COVID-19

N Kappelmann, R Dantzer, GM Khandaker - Psychoneuroendocrinology, 2021 - Elsevier
The majority of COVID-19 survivors experience long-term neuropsychiatric symptoms such
as fatigue, sleeping difficulties, depression and anxiety. We propose that neuroimmune …

Association between systemic inflammation and individual symptoms of depression: a pooled analysis of 15 population-based cohort studies

P Frank, M Jokela, GD Batty, D Cadar… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: Evidence from anti-inflammatory drug trials for the treatment of depression has
been inconsistent. This may be ascribed to the differing symptom-specific effects of …

Using network analysis to examine links between individual depressive symptoms, inflammatory markers, and covariates

EI Fried, S Von Stockert, JMB Haslbeck… - Psychological …, 2020 - cambridge.org
BackgroundStudies investigating the link between depressive symptoms and inflammation
have yielded inconsistent results, which may be due to two factors. First, studies differed …

Inflammatory markers and treatment outcome in treatment resistant depression: a systematic review

C Yang, KJ Wardenaar, FJ Bosker, J Li… - Journal of affective …, 2019 - Elsevier
Background A substantial percentage of depressed patients do not respond satisfactorily to
conventional antidepressant treatment. This treatment resistant depression (TRD) may be …

[HTML][HTML] Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder

C Green, X Shen, AJ Stevenson, ELS Conole… - Brain, behavior, and …, 2021 - Elsevier
Inflammatory processes are implicated in the aetiology of Major Depressive Disorder (MDD);
however, the relationship between peripheral inflammation, brain structure and depression …

Replication and reproducibility issues in the relationship between C-reactive protein and depression: a systematic review and focused meta-analysis

SR Horn, MM Long, BW Nelson, NB Allen… - Brain, behavior, and …, 2018 - Elsevier
One of the most common inflammatory markers examined in depression is C-reactive
protein (CRP). However, the magnitude of the association between CRP and depression …

Basal and LPS-stimulated inflammatory markers and the course of individual symptoms of depression

WA van Eeden, AM van Hemert, IVE Carlier… - Translational …, 2020 - nature.com
Multiple studies show an association between inflammatory markers and major depressive
disorder (MDD). People with chronic low-grade inflammation may be at an increased risk of …