Transcriptional regulation of metastatic [Id] entity by KLF17

MP Iwanicki, JS Brugge - Genome biology, 2009 - Springer
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CD147‑mediated reprogrammed glycolytic metabolism potentially induces immune escape in the tumor microenvironment

X Li, W Xu - Oncology reports, 2019 - spandidos-publications.com
Impaired antitumor immunity or induced immunosuppression in the tumor microenvironment
contributes significantly to tumor progression and resistance to immunotherapy. It is …

KRAS Mutant Tumor Subpopulations can Subvert Durable Responses to Personalized Cancer Treatments

BL Parsons, MB Myers - Personalized Medicine, 2013 - Taylor & Francis
KRAS mutations in colorectal and lung cancers predict failure to respond to therapies that
target the EGFR. Significant percentages of patients with KRAS wild-type tumors also fail to …

Evaluation of nitroreductase activity in nasopharyngeal carcinoma progression by an activatable two-photon fluorescent probe

Y Zou, X Chen, Z Cheng, H Chen, J Wu, H Liu… - Spectrochimica Acta Part …, 2022 - Elsevier
Nasopharyngeal carcinoma (NPC) originating from the epithelium cells is the most common
malignant tumor of the head and neck. Small-molecule fluorescent probes for early …

Radiolabeled probes targeting hypoxia‐inducible factor‐1‐active tumor microenvironments

M Ueda, H Saji - The Scientific World Journal, 2014 - Wiley Online Library
Because tumor cells grow rapidly and randomly, hypoxic regions arise from the lack of
oxygen supply in solid tumors. Hypoxic regions in tumors are known to be resistant to …

Fluorine-18 click radiosynthesis and microPET/CT evaluation of a small peptide-a potential PET probe for carbonic anhydrase IX

L Jia, X Li, D Cheng, L Zhang - Bioorganic & Medicinal Chemistry, 2019 - Elsevier
Abstract Carbonic anhydrase IX (CA IX) is the first carbonic anhydrase found to be
associated with cancer that is over-expressed in a variety of human solid tumors. As a …

[引用][C] 低氧对人肝癌HepG2 细胞中HIF-1α 及miR-210 表达的影响

徐凌, 王锋, 卫巍, 戴维奇, 何珊珊, 王兴鹏, 郭传勇 - 肿瘤, 2011

Rapid detection of hypoxia-inducible factor-1-active tumours: pretargeted imaging with a protein degrading in a mechanism similar to hypoxia-inducible factor-1α

M Ueda, T Kudo, Y Kuge, T Mukai, S Tanaka… - European journal of …, 2010 - Springer
Abstract Purpose Hypoxia-inducible factor-1 (HIF-1) plays an important role in malignant
tumour progression. For the imaging of HIF-1-active tumours, we previously developed a …

Development of an oxygen-sensitive degradable peptide probe for the imaging of hypoxia-inducible factor-1-active regions in tumors

M Ueda, K Ogawa, A Miyano, M Ono… - Molecular imaging and …, 2013 - Springer
Purpose We aimed to develop a radiolabeled peptide probe for the imaging of hypoxia-
inducible factor-1 (HIF-1)-active tumors. Procedures We synthesized the peptide probes that …

Evaluation of [125I]IPOS as a molecular imaging probe for hypoxia‐inducible factor‐1‐active regions in a tumor: Comparison among single‐photon emission …

M Ueda, T Kudo, Y Mutou, IO Umeda, A Miyano… - Cancer …, 2011 - Wiley Online Library
To image hypoxia‐inducible factor‐1 (HIF‐1)‐active tumors, we previously developed a
chimeric protein probe ([123/125I] IPOS) that is degraded in the same manner as HIF‐1α …