Code interpreter for bioinformatics: are we there yet?

L Wang, X Ge, L Liu, G Hu - Annals of Biomedical Engineering, 2024 - Springer
Abstract The Code Interpreter feature in ChatGPT has the potential to democratize data
analysis for non-specialists. As bioinformaticians, we are impressed by its performance in …

[HTML][HTML] Metabolic changes underlying drug resistance in the multiple myeloma tumor microenvironment

M Matamala Montoya, GJJ van Slobbe… - Frontiers in …, 2023 - frontiersin.org
Multiple myeloma (MM) is characterized by the clonal expansion of malignant plasma cells
in the bone marrow (BM). MM remains an incurable disease, with the majority of patients …

Scientific figures interpreted by ChatGPT: strengths in plot recognition and limits in color perception

J Wang, Q Ye, L Liu, NL Guo, G Hu - NPJ Precision Oncology, 2024 - nature.com
Emerging studies underscore the promising capabilities of large language model-based
chatbots in conducting basic bioinformatics data analyses. The recent feature of accepting …

[HTML][HTML] Redox imbalance in COVID-19 pathophysiology

N Majumder, V Deepak, S Hadique, D Aesoph… - Redox biology, 2022 - Elsevier
Background The pathophysiologic significance of redox imbalance is unquestionable as
numerous reports and topic reviews indicate alterations in redox parameters during corona …

Noncoding RNAs in the crosstalk between multiple myeloma cells and bone marrow microenvironment

W Tang, J Xu, C Xu - Cancer Letters, 2023 - Elsevier
Multiple myeloma (MM) is the second most common hematological malignancy; however, it
remains incurable, and the underlying pathogenesis and mechanisms of drug resistance …

Dose-Specific Intratumoral GM-CSF Modulates Breast Tumor Oxygenation and Antitumor Immunity

NE Mihalik, KJ Steinberger, AM Stevens… - The Journal of …, 2023 - journals.aai.org
GM-CSF has been employed as an adjuvant to cancer immunotherapy with mixed results
based on dosage. We previously showed that GM-CSF regulated tumor angiogenesis by …

Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes

M Binder, RE Szalat, S Talluri, M Fulciniti… - Nature …, 2024 - nature.com
The natural history of multiple myeloma is characterized by its localization to the bone
marrow and its interaction with bone marrow stromal cells. The bone marrow stromal cells …

XX sex chromosome complement modulates immune responses to heat-killed Streptococcus pneumoniae immunization in a microbiome-dependent manner

CJ Amato-Menker, Q Hopen, A Pettit, J Gandhi… - Biology of sex …, 2024 - Springer
Background Differences in male vs. female immune responses are well-documented and
have significant clinical implications. While the immunomodulatory effects of sex hormones …

Tetramerization of STAT5 regulates monocyte differentiation and the dextran sulfate sodium-induced colitis in mice

KL Monaghan, W Zheng, H Akhter, L Wang… - Frontiers in …, 2023 - frontiersin.org
In response to external stimuli during immune responses, monocytes can have multifaceted
roles such as pathogen clearance and tissue repair. However, aberrant control of monocyte …

[HTML][HTML] Bioinformatics illustrations decoded by chatgpt: The good, the bad, and the ugly

J Wang, Q Ye, L Liu, NL Guo, G Hu - bioRxiv, 2023 - ncbi.nlm.nih.gov
Emerging studies underscore the promising capabilities of large language model-based
chatbots in conducting fundamental bioinformatics data analyses. The recent feature of …