Management of carcinoid tumors

FC Detterbeck - The Annals of thoracic surgery, 2010 - Elsevier
Primary bronchopulmonary carcinoids comprise a significant proportion of carcinoid tumors.
The clinical presentation allows prediction of the diagnosis and cell type and directs …

Clinical presentation and evaluation of neuroendocrine tumors of the lung

FC Detterbeck - Thoracic Surgery Clinics, 2014 - thoracic.theclinics.com
Neuroendocrine tumors (NETs) of the lung all display neuroendocrine granules on
microscopic examination; however, these tumors cover a wide spectrum. This includes …

Octreoscan in patients with bronchial carcinoid tumours

D Granberg, A Sundin, ET Janson, K Öberg… - Clinical …, 2003 - Wiley Online Library
Summary objectives Scintigraphy with radiolabelled octreotide (octreoscan) is useful for
imaging various neuroendocrine tumours, especially in patients with midgut carcinoids. We …

Expression of somatostatin receptor types 2, 3 and 5 in biopsies and surgical specimens of human lung tumours: Correlation with preoperative octreotide scintigraphy

M Papotti, S Croce, M Bellò, M Bongiovanni, E Allìa… - Virchows Archiv, 2001 - Springer
The increasingly popular use of somatostatin analogs in clinical practice for both diagnostic
and therapeutic purposes prompted extensive investigations on somatostatin receptor (sst) …

Localization and mRNA expression of somatostatin receptor subtypes in human prostatic tissue and prostate cancer cell lines

N Dizeyi, L Konrad, A Bjartell, H Wu… - … Oncology: Seminars and …, 2002 - Elsevier
Somatostatin (SST) plays an important regulatory role in the physiological control of various
organs including the prostate. Somatostatin receptors (SSTRs) and SST analogs are …

A targeted cytotoxic somatostatin (SST) analogue, AN-238, inhibits the growth of H-69 small-cell lung carcinoma (SCLC) and H-157 non-SCLC in nude mice

H Kiaris, AV Schally, A Nagy, K Szepeshazi… - European journal of …, 2001 - Elsevier
Recently, we developed a cytotoxic analogue of somatostatin (SST), AN-238, in which the
SST carrier peptide RC-121 was linked to 2-pyrrolinodoxorubicin (2-pyrrolino-DOX)(AN …

Somatostatin receptor expression in non-classical locations–clinical relevance?

E Bhanat, CA Koch, R Parmar, V Garla… - Reviews in Endocrine …, 2018 - Springer
Abstract In-111 pentetreotide (Octreoscan) is a radiolabeled somatostatin analog with high
binding affinity to somatostatin receptors (SSTR) used in somatostatin receptor scintigraphy …

Radionuclide-based theranostics—a promising strategy for lung cancer

T Zhu, JC Hsu, J Guo, W Chen, W Cai… - European Journal of …, 2023 - Springer
Purpose This review aims to provide a comprehensive overview of the latest literature on
personalized lung cancer management using different ligands and radionuclide-based …

SSTR2-based reporters for assessing gene transfer into non–small cell lung cancer: evaluation using an intrathoracic mouse model

SP Singh, L Han, R Murali, L Solis, J Roth, L Ji… - Human gene …, 2011 - liebertpub.com
The most common cause of cancer-related deaths in North America is lung cancer, 85% of
which is non–small cell lung cancer (NSCLC). Gene therapy is a promising approach, but …

Somatostatin receptor scintigraphy in thoracic diseases

P Ameri, F Gatto, M Arvigo, G Villa, E Resmini… - Journal of …, 2007 - Springer
Somatostatin (SS) receptor scintigraphy is useful for the diagnosis of lesions with high
density of SS receptors, and above all neuroendocrine tumors. For several years, only …