Recent Advances in Momordica charantia: Functional Components and Biological Activities

S Jia, M Shen, F Zhang, J Xie - International journal of molecular sciences, 2017 - mdpi.com
Momordica charantia L.(M. charantia), a member of the Cucurbitaceae family, is widely
distributed in tropical and subtropical regions of the world. It has been used in folk medicine …

Bitter melon: a panacea for inflammation and cancer

PR Dandawate, D Subramaniam, SB Padhye… - Chinese journal of …, 2016 - Elsevier
Nature is a rich source of medicinal plants and their products that are useful for treatment of
various diseases and disorders. Momordica charantia, commonly known as bitter melon or …

[HTML][HTML] MAP30 protein from Momordica charantia is therapeutic and has synergic activity with cisplatin against ovarian cancer in vivo by altering metabolism and …

DW Chan, MMH Yung, YS Chan, Y Xuan… - Pharmacological …, 2020 - Elsevier
Increasing evidence shows that Traditional Chinese Medicine (TCM) has an obvious appeal
for cancer treatment, but there is still a lack of scientific investigation of its underlying …

A mini-review of chemical and biological properties of polysaccharides from Momordica charantia

F Zhang, L Lin, J Xie - International journal of biological macromolecules, 2016 - Elsevier
Recently, isolation and characterization of bioactive polysaccharides from natural resources
have attracted increasing interest. Momordica charantia L.(M. charantia), belongs to the …

Bitter melon (Momordica charantia): a natural healthy vegetable

F Saeed, M Afzaal, B Niaz, MU Arshad… - … Journal of Food …, 2018 - Taylor & Francis
Bitter melon provides health benefits against various ailments for improving the quality of
life. It is nutrient dense plant-based food containing versatility of bioactive compounds such …

Promise of bitter melon (Momordica charantia) bioactives in cancer prevention and therapy

K Raina, D Kumar, R Agarwal - Seminars in cancer biology, 2016 - Elsevier
Recently, there is a paradigm shift that the whole food-derived components are not 'idle
bystanders' but actively participate in modulating aberrant metabolic and signaling pathways …

The MAP30 protein from bitter gourd (Momordica charantia) seeds promotes apoptosis in liver cancer cells in vitro and in vivo

EF Fang, CZY Zhang, JH Wong, JY Shen, CH Li, TB Ng - Cancer letters, 2012 - Elsevier
Human hepatocellular carcinoma Hep G2 cells and Hep G2-bearing mice were used as in
vitro and in vivo models to assess the efficacy and safety of MAP30, a natural component …

Momordica charantia (Bitter Melon) Reduces Obesity-Associated Macrophage and Mast Cell Infiltration as well as Inflammatory Cytokine Expression in Adipose …

B Bao, YG Chen, L Zhang, YL Na Xu, X Wang, J Liu… - PloS one, 2013 - journals.plos.org
Obesity is a world-wide epidemic disease that correlates closely with type 2 diabetes and
cardiovascular diseases. Obesity-induced chronic adipose tissue inflammation is now …

Momordica Charantia lectin, a type II ribosome inactivating protein, exhibits antitumor activity toward human nasopharyngeal carcinoma cells in vitro and in vivo

EF Fang, CZY Zhang, TB Ng, JH Wong, WL Pan… - Cancer Prevention …, 2012 - AACR
The incidence of nasopharyngeal carcinoma (NPC) remains high in endemic regions,
including southern China, northern Africa, and North America. One of the promising …

[HTML][HTML] Momordica charantia Extract Induces Apoptosis in Human Cancer Cells through Caspase- and Mitochondria-Dependent Pathways

CJ Li, SF Tsang, CH Tsai, HY Tsai… - Evidence-Based …, 2012 - hindawi.com
Plants are an invaluable source of potential new anti-cancer drugs. Momordica charantia is
one of these plants with both edible and medical value and reported to exhibit anticancer …