Diverse subtypes of renal cell carcinomas (RCCs) display a wide spectrum of
histomorphologies, proteogenomic alterations, immune cell infiltration patterns, and clinical …

Characterised by high intra‐and inter‐tumor heterogeneity, metastatic renal cell carcinoma
(RCC) is resistant to chemo‐and radiotherapy. Therefore, the development of new …

A kidney is an organ with relatively low basal cellular regenerative potential. However, renal
cells have a pronounced ability to proliferate after injury, which undermines that the kidney …

The pressure towards innovation and creation of new model systems in regenerative
medicine and cancer research has fostered the development of novel potential therapeutic …

Human urine is a non-invasive source of renal stem cells with regeneration potential. Urine-
derived renal progenitor cells were isolated from 10 individuals of both genders and distinct …

Simple Summary Several current therapies fail to eradicate tumors due to the ability of
cancer stem cells (CSCs) to escape different programmed cell deaths. In fact, apoptosis …

The decrease in the number of resident progenitor cells with age was shown for several
organs. Such a loss is associated with a decline in regenerative capacity and a greater …

Nephropathic cystinosis is an inherited lysosomal storage disorder caused by pathogenic
variants in the cystinosin (CTNS) gene and is characterized by the excessive shedding of …

Background Nestin is an intermediate filament first reported in neuroepithelial stem cells.
Nestin expression could be found in a variety of tissues throughout all systems of the body …

The kidney is a complicated and important internal organ receiving approximately 20% of
the cardiac output and mediates numerous pathophysiologic actions. These include …