Overview of the 2022 WHO classification of thyroid neoplasms

ZW Baloch, SL Asa, JA Barletta, RA Ghossein… - Endocrine …, 2022 - Springer
This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

Emerging biomarkers in thyroid practice and research

S Agarwal, A Bychkov, CK Jung - Cancers, 2021 - mdpi.com
Simple Summary Tumor biomarkers are molecules at genetic or protein level, or certain
evaluable characteristics. These help in perfecting patient management. Over the past …

A shift in molecular drivers of papillary thyroid carcinoma following the 2017 World health organization classification: characterization of 554 consecutive tumors with …

JF Hang, JY Chen, PC Kuo, HF Lai, TL Lee, SK Tai… - Modern Pathology, 2023 - Elsevier
Most studies for comprehensive molecular profiling of papillary thyroid carcinoma (PTC)
have been performed before the 2017 World Health Organization (WHO) classification, in …

Expanding the spectrum of thyroid carcinoma with somatic DICER1 mutation: a survey of 829 thyroid carcinomas using MSK-IMPACT next-generation sequencing …

CA Ghossein, S Dogan, N Farhat, I Landa, B Xu - Virchows Archiv, 2022 - Springer
DICER1 gene encodes an RNaseIII endoribonuclease essential for the cleavage of pre-
microRNA to mature microRNA. Germline DICER1 mutation results in DICER syndrome, a …

DICER1 Mutations Occur in More Than One-Third of Follicular-Patterned Pediatric Papillary Thyroid Carcinomas and Correlate with a Low-Risk Disease and Female …

S Onder, O Mete, I Yilmaz, A Bayram, S Bagbudar… - Endocrine …, 2022 - Springer
Some pediatric papillary thyroid carcinoma (PPTC) cohorts have suggested a preliminary
correlation with respect to DICER1 mutation status and histomorphology in both benign and …

Expanding Our Knowledge of DICER1 Gene Alterations and Their Role in Thyroid Diseases

MC Riascos, A Huynh, WC Faquin, V Nosé - Cancers, 2024 - mdpi.com
Simple Summary Mutations in DICER1, a gene involved in RNA interference, have been
associated with a wide range of multi-organ neoplastic and non-neoplastic conditions …

On the chopping block: overview of DICER1 mutations in endocrine and neuroendocrine neoplasms

CC Juhlin - Surgical Pathology Clinics, 2023 - surgpath.theclinics.com
Mutational inactivation of the DICER1 gene causes aberrant micro-RNA maturation, which in
turn may have consequences for the posttranscriptional regulation of gene expression …

Genetic alterations landscape in paediatric thyroid tumours and/or differentiated thyroid cancer: Systematic review

MSA de Sousa, IN Nunes, YP Christiano… - Reviews in Endocrine …, 2024 - Springer
Differentiated thyroid cancer (DTC) is a rare disease in the paediatric population (≤ 18
years old. at diagnosis). Increasing incidence is reflected by increases in incidence for …

Molecular landscape of pediatric thyroid cancer: a review

P Guleria, R Srinivasan, C Rana, S Agarwal - Diagnostics, 2022 - mdpi.com
Thyroid carcinomas (TC) are rare in the pediatric population; however, they constitute the
most common endocrine malignancy. Despite some similarities with adult carcinomas, they …

Genomic and transcriptomic analyses of thyroid cancers identify DICER1 somatic mutations in adult follicular-patterned RAS-like tumors

E Minna, A Devecchi, F Pistore, B Paolini… - Frontiers in …, 2023 - frontiersin.org
Background Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer
(TC). Several genomic and transcriptomic studies explored the molecular landscape of …