Role of histone modifications in neurogenesis and neurodegenerative disease development

A Zhao, W Xu, R Han, J Wei, Q Yu, M Wang, H Li… - Ageing Research …, 2024 - Elsevier
Progressive neuronal dysfunction and death are key features of neurodegenerative
diseases; therefore, promoting neurogenesis in neurodegenerative diseases is crucial. With …

Epigenome-wide association study of peripheral immune cell populations in Parkinson's disease

MS Andersen, IS Leikfoss, IS Brorson… - npj Parkinson's …, 2023 - nature.com
Understanding the contribution of immune mechanisms to Parkinson's disease
pathogenesis is an important challenge, potentially of major therapeutic implications. To …

Melatonin-Loaded Nanoparticles Augment Mitophagy to Retard Parkinson's Disease

L Biswal, MN Sardoiwala, AC Kushwaha… - … Applied Materials & …, 2024 - ACS Publications
The molecular pathways that melatonin follows as a Parkinson's disease (PD) antagonist
remain poorly elucidated, despite it being a safe and a potential neurotherapeutic drug with …

[HTML][HTML] Interplay of human gastrointestinal microbiota metabolites: Short-chain fatty acids and their correlation with Parkinson's disease

J Liu, Q Chen, R Su - Medicine, 2024 - journals.lww.com
Short-chain fatty acids (SCFAs) are, the metabolic byproducts of intestinal microbiota that,
are generated through anaerobic fermentation of undigested dietary fibers. SCFAs play a …

Epigenetics: the missing link between environmental exposures and Parkinson's disease?

E Angelopoulou, C Piperi - Epigenomics, 2024 - Taylor & Francis
Parkinson's disease (PD) presents one of the most common neurodegenerative movement
disorders with a clinically heterogeneous phenotype and ambiguous pathological …

Cardiovascular history and risk of idiopathic Parkinson's disease: a cross-sectional observational study

S Acharya, AI Lumley, Y Devaux - BMC neuroscience, 2024 - Springer
Background Parkinson's disease (PD), while often associated with its distinctive motor
symptoms, can also exert a notable impact on the cardiovascular system due to the …

Epigenetic Alterations of Cognition Functions in Parkinson's Disease

F Hasani, P Ahmadi, M Masrour, S Khamaki… - 2024 - preprints.org
The field of epigenetics, which explores how heritable traits or stable alterations of cell
functions occur without changes to the DNA sequence and how environmental factors affect …