Managing chronic neuropathic pain: recent advances and new challenges

N Hange, S Poudel, S Ozair, T Paul… - Neurology Research …, 2022 - Wiley Online Library
Aim. Neuropathic pain affects 7–10% of the population, with most of the patients receiving
inadequate and incomplete treatment. Owing to the high financial burden and the poor …

Stem cells in the treatment of neuropathic pain: research progress of mechanism

M Liu, K Li, Y Wang, G Zhao, J Jiang - Stem Cells International, 2020 - Wiley Online Library
Neuropathic pain (NP) is pain caused by somatosensory nervous system injury or disease.
Its prominent symptoms are spontaneous pain, hyperalgesia, and allodynia, and the sense …

Conditioned medium of bone marrow‐derived mesenchymal stromal cells as a therapeutic approach to neuropathic pain: A preclinical evaluation

KB Gama, DS Santos, AF Evangelista… - Stem Cells …, 2018 - Wiley Online Library
Neuropathic pain is a type of chronic pain caused by injury or dysfunction of the nervous
system, without effective therapeutic approaches. Mesenchymal stromal cells (MSCs) …

Recent advances of stem cell therapy for retinitis pigmentosa

Y He, Y Zhang, X Liu, E Ghazaryan, Y Li, J Xie… - International journal of …, 2014 - mdpi.com
Retinitis pigmentosa (RP) is a group of inherited retinal disorders characterized by
progressive loss of photoreceptors and eventually leads to retina degeneration and atrophy …

Synergic effect of early administration of probiotics and adipose-derived mesenchymal stem cells on alleviating inflammation-induced chronic neuropathic pain in …

KH Chen, HS Lin, YC Li, PH Sung, YL Chen… - International Journal of …, 2022 - mdpi.com
This study investigated the hypothesis that probiotics enhanced the therapeutic effect of
adipose-derived mesenchymal stem cells (ADMSCs) on alleviating neuropathic pain (NP) …

Fe3O4@Polydopamine-Labeled MSCs Targeting the Spinal Cord to Treat Neuropathic Pain Under the Guidance of a Magnetic Field

M Liu, W Yu, F Zhang, T Liu, K Li, M Lin… - International Journal …, 2021 - Taylor & Francis
Purpose Neuropathic pain causes great distress among patients; however, its response to
traditional analgesia techniques remains sub-optimal. There has been progress in stem cell …

The role of fat grafting in alleviating neuropathic pain: a critical review of the literature

M Alessandri-Bonetti, FM Egro… - … Surgery–Global Open, 2019 - journals.lww.com
Background: Neuropathic pain is one of the more severe types of chronic pain and presents
a great challenge as response to medical therapy remains often unpredictable. With the …

Intrathecal injection of human umbilical cord-derived mesenchymal stem cells ameliorates neuropathic pain in rats

C Chen, F Chen, C Yao, S Shu, J Feng, X Hu… - Neurochemical …, 2016 - Springer
Neuropathic pain (NP) is a clinically incurable disease with miscellaneous causes,
complicated mechanisms and available therapies show poor curative effect. Some recent …

Injectable biologics for neuropathic pain: A systematic review

M Bies, Z Ashmore, W Qu, C Hunt - Pain Medicine, 2022 - academic.oup.com
Background Neuropathic pain is a complex condition that can be refractory to conventional
management and can cause persistent suffering in patients. Current pharmacologic …

Analgesia for neuropathic pain by dorsal root ganglion transplantation of genetically engineered mesenchymal stem cells: initial results

H Yu, G Fischer, AD Ebert, HE Wu, X Bai… - Molecular …, 2015 - journals.sagepub.com
Background Cell-based therapy may hold promise for treatment of chronic pain.
Mesenchymal stem cells (MSCs) are readily available and robust, and their secretion of …