Recent genetics and epigenetics approaches to PTSD

NP Daskalakis, CM Rijal, C King, LM Huckins… - Current psychiatry …, 2018 - Springer
Abstract Purpose of Review Following a life-threatening traumatic exposure, about 10% of
those exposed are at considerable risk for developing posttraumatic stress disorder (PTSD) …

[HTML][HTML] A scoping review of guidelines for the use of race, ethnicity, and ancestry reveals widespread consensus but also points of ongoing disagreement

M Mauro, DS Allen, B Dauda, SJ Molina… - The American Journal of …, 2022 - cell.com
The use of population descriptors such as race, ethnicity, and ancestry in science, medicine,
and public health has a long, complicated, and at times dark history, particularly for genetics …

[HTML][HTML] The great migration and African-American genomic diversity

S Baharian, M Barakatt, CR Gignoux… - PLoS …, 2016 - journals.plos.org
We present a comprehensive assessment of genomic diversity in the African-American
population by studying three genotyped cohorts comprising 3,726 African-Americans from …

Protective alleles and modifier variants in human health and disease

AR Harper, S Nayee, EJ Topol - Nature Reviews Genetics, 2015 - nature.com
The combination of next-generation sequencing technologies and high-throughput
genotyping platforms has revolutionized the pursuit of genetic variants that contribute …

[HTML][HTML] Defining and achieving health equity in genomic medicine

S Jooma, MJ Hahn, LA Hindorff, VL Bonham - Ethnicity & disease, 2019 - ncbi.nlm.nih.gov
The potential of genomics to improve health comes with the peril that the benefits will not be
equitably available to all populations. Existing health disparities can be exacerbated if the …

Socioeconomic status associates with worse asthma morbidity among Black and Latinx adults

JC Cardet, KL Chang, BJ Rooks, JK Carroll… - Journal of Allergy and …, 2022 - Elsevier
Background Asthma disproportionately affects African American/Black (AA/B) and
Hispanic/Latinx (H/L) patients and individuals with low socioeconomic status (SES), but the …

Admixture in latin america

K Adhikari, J Mendoza-Revilla… - Current opinion in …, 2016 - Elsevier
Latin Americans arguably represent the largest recently admixed populations in the world.
This reflects a history of massive settlement by immigrants (mostly Europeans and Africans) …

Meeting the needs of underserved populations: setting the agenda for more inclusive citizen science of medicine

A Fiske, B Prainsack, A Buyx - Journal of medical ethics, 2019 - jme.bmj.com
In its expansion to genomic, epidemiological and biomedical research, citizen science has
been promoted as contributing to the democratisation of medical research and healthcare …

Novel genetic risk factors for asthma in African American children: Precision Medicine and the SAGE II Study

MJ White, O Risse-Adams, P Goddard, MG Contreras… - Immunogenetics, 2016 - Springer
Asthma, an inflammatory disorder of the airways, is the most common chronic disease of
children worldwide. There are significant racial/ethnic disparities in asthma prevalence …

[HTML][HTML] Mexican-American perspectives on participation in clinical trials: A qualitative study

M Arevalo, NI Heredia, S Krasny, ML Rangel… - Contemporary clinical …, 2016 - Elsevier
Clinical trials are essential to advancing knowledge to reduce disease morbidity and
mortality; however, ethnic and racial minorities remain under-represented in those studies …