Nontuberculous mycobacterial lung disease caused by Mycobacterium avium complex - disease burden, unmet needs, and advances in treatment developments
J van Ingen, M Obradovic, M Hassan… - Expert Review of …, 2021 - Taylor & Francis
Introduction Nontuberculous mycobacterial (NTM) lung disease (LD) is the most common
clinical manifestation of NTM infection and is a growing health concern. Up to 85% of NTM …
clinical manifestation of NTM infection and is a growing health concern. Up to 85% of NTM …
A narrative review of nontuberculous mycobacterial pulmonary disease: Microbiology, epidemiology, diagnosis, and management challenges
KA Hamed, G Tillotson - Expert Review of Respiratory Medicine, 2023 - Taylor & Francis
Introduction Nontuberculous mycobacteria (NTM) are a diverse group of mycobacterial
species that are ubiquitous in the environment. They are opportunistic pathogens that can …
species that are ubiquitous in the environment. They are opportunistic pathogens that can …
Whole genome sequencing in the management of non-tuberculous mycobacterial infections
Infections caused by non-tuberculous mycobacteria (NTM) have been a public health
problem in recent decades and contribute significantly to the clinical and economic burden …
problem in recent decades and contribute significantly to the clinical and economic burden …
Synthesis and Characterization of Phenylalanine Amides Active against Mycobacterium abscessus and Other Mycobacteria
M Lang, US Ganapathy, L Mann… - Journal of medicinal …, 2023 - ACS Publications
N α-2-thiophenoyl-d-phenylalanine-2-morpholinoanilide [MMV688845, Pathogen Box;
Medicines for Malaria Venture; IUPAC:(2 R)-N-(1-((2-morpholinophenyl) amino)-1-oxo-3 …
Medicines for Malaria Venture; IUPAC:(2 R)-N-(1-((2-morpholinophenyl) amino)-1-oxo-3 …
[HTML][HTML] The respiratory microbiome and nontuberculous mycobacteria: an emerging concern in human health
CS Thornton, M Mellett, J Jarand… - European …, 2021 - Eur Respiratory Soc
Nontuberculous mycobacteria (NTM) are diverse microbial species encompassing
commensals and pathogens with the ability to cause pulmonary disease in both …
commensals and pathogens with the ability to cause pulmonary disease in both …
[HTML][HTML] Addressing antimicrobial resistance with the IDentif. AI platform: Rapidly optimizing clinically actionable combination therapy regimens against …
Background: Current standard of care (SOC) regimens against nontuberculous
mycobacteria (NTM) usually result in unsatisfactory therapeutic responses, primarily due to …
mycobacteria (NTM) usually result in unsatisfactory therapeutic responses, primarily due to …
[HTML][HTML] Prevalence and speciation of non-tuberculous mycobacteria among pulmonary and extrapulmonary tuberculosis suspects in South India
K Thangavelu, K Krishnakumariamma, G Pallam… - Journal of Infection and …, 2021 - Elsevier
Background and objectives Non tuberculous mycobacteria (NTM) is an emerging
opportunistic pathogen increasing globally and indistinguishable from tuberculosis (TB) …
opportunistic pathogen increasing globally and indistinguishable from tuberculosis (TB) …
The first diagnostic test for specific detection of Mycobacterium simiae using an electrochemical label-free DNA nanobiosensor
Mycobacterium simiae has been reported to be the most prevalent species of
Nontuberculous mycobacteria (NTM) in many countries. As both phenotypic and molecular …
Nontuberculous mycobacteria (NTM) in many countries. As both phenotypic and molecular …
In Vitro Profiling of the Synthetic RNA Polymerase Inhibitor MMV688845 against Mycobacterium abscessus
L Mann, US Ganapathy, R Abdelaziz… - Microbiology …, 2022 - Am Soc Microbiol
In a library screen of tuberculosis-active compounds for anti-Mycobacterium abscessus
activity, we previously identified the synthetic phenylalanine amide MMV688845. In …
activity, we previously identified the synthetic phenylalanine amide MMV688845. In …
Soil properties and moisture synergistically influence nontuberculous mycobacterial prevalence in natural environments of Hawai'i
AW Parsons, SN Dawrs, ST Nelson… - Applied and …, 2022 - Am Soc Microbiol
Nontuberculous mycobacteria (NTM) are opportunistic pathogens that cause chronic
pulmonary disease (PD). NTM infections are thought to be acquired from the environment; …
pulmonary disease (PD). NTM infections are thought to be acquired from the environment; …