[HTML][HTML] Molecular mechanisms and therapeutic targets for diabetic kidney disease

KR Tuttle, R Agarwal, CE Alpers, GL Bakris… - Kidney international, 2022 - Elsevier
Diabetic kidney disease has a high global disease burden and substantially increases the
risk of kidney failure and cardiovascular events. Despite treatment, there is substantial …

Obesity I: Overview and molecular and biochemical mechanisms

RH Lustig, D Collier, C Kassotis, TA Roepke… - Biochemical …, 2022 - Elsevier
Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …

Microgreens—A comprehensive review of bioactive molecules and health benefits

M Bhaswant, DK Shanmugam, T Miyazawa, C Abe… - Molecules, 2023 - mdpi.com
Microgreens, a hypothesized term used for the emerging food product that is developed from
various commercial food crops, such as vegetables, grains, and herbs, consist of developed …

METTL14 is required for exercise-induced cardiac hypertrophy and protects against myocardial ischemia-reperfusion injury

L Wang, J Wang, P Yu, J Feng, G Xu, X Zhao… - Nature …, 2022 - nature.com
RNA m6A modification is the most widely distributed RNA methylation and is closely related
to various pathophysiological processes. Although the benefit of regular exercise on the …

Effect of calorie-unrestricted low-carbohydrate, high-fat diet versus high-carbohydrate, low-fat diet on type 2 diabetes and nonalcoholic fatty liver disease: a …

CD Hansen, EM Gram-Kampmann… - Annals of Internal …, 2023 - acpjournals.org
Background: It remains unclear if a low-carbohydrate, high-fat (LCHF) diet is a possible
treatment strategy for type 2 diabetes mellitus (T2DM), and the effect on nonalcoholic fatty …

Gut microbiota: A new target for T2DM prevention and treatment

L Liu, J Zhang, Y Cheng, M Zhu, Z Xiao… - Frontiers in …, 2022 - frontiersin.org
Type 2 diabetes mellitus (T2DM), one of the fastest growing metabolic diseases, has been
characterized by metabolic disorders including hyperglycemia, hyperlipidemia and insulin …

Plasma metabolite profiles related to plant-based diets and the risk of type 2 diabetes

F Wang, MY Baden, M Guasch-Ferré, C Wittenbecher… - Diabetologia, 2022 - Springer
Aims/hypothesis Plant-based diets, especially when rich in healthy plant foods, have been
associated with a lower risk of type 2 diabetes. However, whether plasma metabolite profiles …

[HTML][HTML] Management of diabesity: Current concepts

M Michaelidou, JM Pappachan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
The global prevalence of obesity is increasing rapidly with an exponential rise in incidence
of type 2 diabetes mellitus in recent years.'Diabesity', the term coined to show the strong …

[HTML][HTML] Pathophysiology of obesity and its associated diseases

X Jin, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud… - … Pharmaceutica Sinica B, 2023 - Elsevier
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

Bioinspired pH-Responsive Microalgal Hydrogels for Oral Insulin Delivery with Both Hypoglycemic and Insulin Sensitizing Effects

C Ren, D Zhong, Y Qi, C Liu, X Liu, S Chen, S Yan… - ACS …, 2023 - ACS Publications
The oral form of insulin is more convenient and has better patient compliance than
subcutaneous or intravenous insulin. Current oral insulin preparations, however, cannot …