Potential chemopreventive effects of dietary combination of phytochemicals against cancer development

T Tanaka, R Aoki, M Terasaki - Pharmaceuticals, 2023 - mdpi.com
Cancer remains a major cause of cancer-related death worldwide. Over 70% of epithelial
malignancies are sporadic and are related to lifestyle. Epidemiological studies suggest an …

A Review of The Application of Spectroscopy to Flavonoids from Medicine and Food Homology Materials

L Zou, H Li, X Ding, Z Liu, D He, JAH Kowah, L Wang… - Molecules, 2022 - mdpi.com
Medicinal and food homology materials are a group of drugs in herbal medicine that have
nutritional value and can be used as functional food, with great potential for development …

Preparation and evaluation of diosmin-loaded diphenylcarbonate-cross-linked cyclodextrin nanosponges for breast cancer therapy

MK Anwer, MM Ahmed, MF Aldawsari, M Iqbal… - Pharmaceuticals, 2022 - mdpi.com
In the current study, diosmin (DSM)-loaded beta-cyclodextrin (β-CD)-based nanosponges
(NSPs) using diphenylcarbonate (DPC) as a cross-linker were prepared. Four different DSM …

Antioxidant potential of diosmin and diosmetin against oxidative stress in endothelial cells

M Wójciak, M Feldo, G Borowski, T Kubrak, BJ Płachno… - Molecules, 2022 - mdpi.com
Phlebotropic flavonoids, including diosmin and its aglycone diosmetin, are natural
polyphenols widely used in the prevention and treatment of chronic venous insufficiency …

Natural Deep Eutectic Solvent Optimization to Obtain an Extract Rich in Polyphenols from Capsicum chinense Leaves Using an Ultrasonic Probe

KA Avilés-Betanzos, JV Cauich-Rodríguez… - Processes, 2023 - mdpi.com
Capsicum chinense Jacq., from the Yucatan peninsula, is recognized worldwide for its
pungency, flavor, and secondary metabolites content. This has resulted in an increase in its …

Identification of diosmin and flavin adenine dinucleotide as repurposing treatments for monkeypox virus: a computational study

TP Lam, VH Tran, TT Mai, NVT Lai, BTN Dang… - International Journal of …, 2022 - mdpi.com
The World Health Organization declared monkeypox a global public health emergency on
23 July 2022. This disease was caused by the monkeypox virus (MPXV), which was first …

An approach for systems-level understanding of prostate cancer from high-throughput data integration to pathway modeling and simulation

M Mobashir, SP Turunen, MA Izhari, IM Ashankyty… - Cells, 2022 - mdpi.com
To understand complex diseases, high-throughput data are generated at large and multiple
levels. However, extracting meaningful information from large datasets for comprehensive …

Diosmin exerts hepatoprotective and antihyperglycemic effects against sodium arsenite-induced toxicity through the modulation of oxidative stress and inflammation in …

M Mirzaei, M Moosavi, E Mansouri, S Mohtadi… - Journal of Trace …, 2023 - Elsevier
Background Chronic exposure to high concentrations of inorganic arsenic (NaAsO 2) in
drinking water is related to an increase in the risk of liver toxicity and diabetes. Diosmin has …

Genomic profiling and network-level understanding uncover the potential genes and the pathways in hepatocellular carcinoma

SA El-Kafrawy, MM El-Daly, LH Bajrai… - Frontiers in …, 2022 - frontiersin.org
Data integration with phenotypes such as gene expression, pathways or function, and
protein-protein interactions data has proven to be a highly promising technique for …

Diosmin and bromelain stimulate glutathione and total thiols production in red blood cells

L Gwozdzinski, J Bernasinska-Slomczewska… - Molecules, 2023 - mdpi.com
Diosmin and bromelain are bioactive compounds of plant origin with proven beneficial
effects on the human cardiovascular system. We found that diosmin and bromelain slightly …