Background: Phosphoinositide 3-kinase (PI3Ks) is a member of intracellular lipid kinases
and involved in the regulation of cellular proliferation, differentiation and survival …

Colorectal cancer (CRC) is the fourth leading cause of the worldwide cancer mortality.
Different molecular mechanisms have been attributed to the development and progress of …

Colorectal cancer (CRC) is the third most frequently detected type of cancer, and the second
most common cause of cancer-related mortality globally. The American Cancer Society …

Background/Aims: MicroRNA-21 (miR-21) has been demonstrated to play an important role
in carcinogenesis; however, its mechanism of action in colorectal cancer (CRC) has not …

Colorectal cancer (CRC) is the third leading cause of cancer death in the world, and its
incidence is rising in developing countries. Treatment with 5-Fluorouracil (5-FU) is known to …

Colorectal cancer (CRC) is among the top three cancer with higher incident and mortality
rate worldwide. It is estimated that about over than 1.1 million of death and 2.2 million new …

Purpose Tumor purity is defined as the proportion of cancer cells in the tumor tissue. The
impact of tumor purity on colon cancer (CC) prognosis, genetic profile, and …

Abstract The plant Sophora flavescens Ait. has been used in the clinical management of
colorectal cancer (CRC). Its constituent compounds, notably the alkaloids matrine …

Small nucleolar RNA (snoRNA) dysfunctions have been associated with cancer
development. SNORD126 is an orphan C/D box snoRNA that is encoded within introns 5–6 …

This study aimed to evaluate the in vitro effects of syringic acid on human colorectal cancer
cells (SW-480) and the effect of orally administered syringic acid on in vivo models of …