Activation of c-fos in the brain

DG Herrera, HA Robertson - Progress in neurobiology, 1996 - Elsevier
Activation of the proto-oncogene c-fos in the brain was described initially almost a decade
ago and represents one of the most studied immediate early genes in the brain. Transient c …

Fos: an immediate‐early transcription factor in neurons

T Curran, JI Morgan - Journal of neurobiology, 1995 - Wiley Online Library
In the past several years a great deal of evidence has accumulated linking neuronal
activation events to the regulation of gene expression. We have pursued an analysis of c‐fos …

Bone and haematopoietic defects in mice lacking c-fos

ZQ Wang, C Ovitt, AE Grigoriadis, U Möhle-Steinlein… - Nature, 1992 - nature.com
THE proto-oncogene c-fos is the cellular homologue of v-fos originally isolated from murine
osteosarcoma1. Fos protein is a major component of the AP-1 transcription factor complex …

Continuous c-fos expression precedes programmed cell death in vivo

RJ Smeyne, M Vendrell, M Hayward, SJ Baker… - Nature, 1993 - nature.com
THE development of a multicellular organism involves a delicate balance among the
processes of proliferation, differentiation and death. Naturally occurring cell death aids …

[PDF][PDF] c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins

RP Ryseck, R Bravo - Oncogene, 1991 - researchgate.net
We have compared the binding properties of c-JUN, JUN B, and JUN D in the absence or in
the presence of c-FOS, FOS B, and FRA-1 to different AP-1 and CRE-containing …

Osteoblasts are target cells for transformation in c-fos transgenic mice

AE Grigoriadis, K Schellander, ZQ Wang… - The Journal of cell …, 1993 - rupress.org
We have generated transgenic mice expressing the proto-oncogene c-fos from an H-2Kb
class I MHC promoter as a tool to identify and isolate cell populations which are sensitive to …

Transcriptional autoregulation of the proto-oncogene fos

P Sassone-Corsi, JC Sisson, IM Verma - Nature, 1988 - nature.com
Serum-induced transcription of the proto-oncogene fos is under negative feedback
regulation mediated by the fos protein. The fos promoter region responsive to repression is …

Fos-IacZ transgenic mice: mapping sites of gene induction in the central nervous system

RJ Smeyne, K Schilling, L Robertson, D Luk… - Neuron, 1992 - cell.com
A transgenic mouse line containing a fos-/acZ fusion gene was derived in which (3-
galactosidase activity identified cell populations expressing fos either constitutively or after …

Transformation by ras modifies AP1 composition and activity

F Mechta, D Lallemand, CM Pfarr, M Yaniv - Oncogene, 1997 - nature.com
The Ras proteins play a central role in regulating cell growth and their mutation can lead to
abnormal proliferation. To analyse the potential link betwen AP1 activity, encoded by …

Hox‐7, a mouse homeobox gene with a novel pattern of expression during embryogenesis.

B Robert, D Sassoon, B Jacq, W Gehring… - The EMBO …, 1989 - embopress.org
A new mouse Hox locus, Hox‐7, is defined on chromosome 5 by a gene homologous to the
Drosophila gene msh, which contains a homeobox sequence distantly related to that of …