Serrated lesions of the colorectum: review and recommendations from an expert panel

DK Rex, DJ Ahnen, JA Baron, KP Batts… - Official journal of the …, 2012 - journals.lww.com
Serrated lesions of the colorectum are the precursors of perhaps one-third of colorectal
cancers (CRCs). Cancers arising in serrated lesions are usually in the proximal colon, and …

Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management

C Rosty, DG Hewett, IS Brown, BA Leggett… - Journal of …, 2013 - Springer
Approximately 30% of colorectal carcinomas develop via the serrated neoplasia pathway
characterized by widespread DNA methylation and frequent BRAF mutation. Serrated …

Post-polypectomy colonoscopy surveillance: European Society of Gastrointestinal Endoscopy (ESGE) guideline

C Hassan, E Quintero, JM Dumonceau, J Regula… - …, 2013 - thieme-connect.com
This Guideline is an official statement of the European Society of Gastrointestinal Endoscopy
(ESGE). The Grading of Recommendations Assessment, Development, and Evaluation …

Serrated and adenomatous polyp detection increases with longer withdrawal time: results from the New Hampshire Colonoscopy Registry

L Butterly, CM Robinson, JC Anderson… - Official journal of the …, 2014 - journals.lww.com
OBJECTIVES: Detection and removal of adenomas and clinically significant serrated polyps
(CSSPs) is critical to the effectiveness of colonoscopy in preventing colorectal cancer …

A morphologic analysis of sessile serrated polyps observed during routine colonoscopy (with video)

US Tadepalli, D Feihel, KM Miller, SH Itzkowitz… - Gastrointestinal …, 2011 - Elsevier
BACKGROUND: Proximal colorectal cancer may arise from sessile serrated polyps (SSPs),
which are often inconspicuous during colonoscopy. The gross morphologic characteristics of …

Serrated lesions in colorectal cancer screening: detection, resection, pathology and surveillance

JE East, M Vieth, DK Rex - Gut, 2015 - gut.bmj.com
A strong evidence base supports colorectal cancer screening. Interruption of the adenoma-
carcinoma sequence by endoscopic polypectomy has been considered the key step in …

Differences in proximal serrated polyp detection among endoscopists are associated with variability in withdrawal time

TR de Wijkerslooth, EM Stoop, PM Bossuyt… - Gastrointestinal …, 2013 - Elsevier
BACKGROUND: Insufficient detection of proximal serrated polyps (PSP) might explain the
occurrence of a proportion of interval carcinomas in colonoscopy surveillance programs …

Serrated colon polyps as precursors to colorectal cancer

S Sweetser, TC Smyrk, FA Sinicrope - Clinical Gastroenterology and …, 2013 - Elsevier
Identification of the serrated neoplasia pathway has improved our understanding of the
pathogenesis of colorectal cancer (CRC). Insights include an increased recognition of the …

Genetics and genetic testing in hereditary colorectal cancer

EM Stoffel, CR Boland - Gastroenterology, 2015 - Elsevier
Colorectal cancer (CRC) remains the third most common cancer affecting men and women
in the United States. Approximately one-third of CRCs are diagnosed in individuals who …

Sessile serrated adenomas: an evidence-based guide to management

SD Crockett, DC Snover, DJ Ahnen, JA Baron - Clinical Gastroenterology …, 2015 - Elsevier
The concept of serrated colorectal neoplasia and a serrated pathway to colorectal cancer
(CRC) is relatively new and continuing to evolve, but it has become highly relevant to …