Exploring the synthetic biology potential of bacteriophages for engineering non-model bacteria

EM Lammens, PI Nikel, R Lavigne - Nature communications, 2020 - nature.com
Non-model bacteria like Pseudomonas putida, Lactococcus lactis and other species have
unique and versatile metabolisms, offering unique opportunities for Synthetic Biology …

Lactococcus lactis, a bacterium with probiotic functions and pathogenicity

F Wu, X Xie, T Du, X Jiang, W Miao, T Wang - World Journal of …, 2023 - Springer
Lactococcus lactis (L. lactis) is the primary organism for lactic acid bacteria (LAB) and is a
globally recognized safe microorganism for the regulation of the intestinal micro-ecological …

Cheesomics: the future pathway to understanding cheese flavour and quality

R Afshari, CJ Pillidge, DA Dias… - Critical Reviews in …, 2020 - Taylor & Francis
Cheese is a fermented dairy product, harboring diverse microbial communities (microbiota)
that change over time and vary depending on the type of cheese and their respective starter …

Omics approaches to assess flavor development in cheese

R Anastasiou, M Kazou, M Georgalaki, A Aktypis… - Foods, 2022 - mdpi.com
Cheese is characterized by a rich and complex microbiota that plays a vital role during both
production and ripening, contributing significantly to the safety, quality, and sensory …

Cell wall homeostasis in lactic acid bacteria: threats and defences

B Martínez, A Rodríguez, S Kulakauskas… - FEMS microbiology …, 2020 - academic.oup.com
Lactic acid bacteria (LAB) encompasses industrially relevant bacteria involved in food
fermentations as well as health-promoting members of our autochthonous microbiota. In the …

Lifestyle, metabolism and environmental adaptation in Lactococcus lactis

M Kleerebezem, H Bachmann… - FEMS Microbiology …, 2020 - academic.oup.com
Lactococcus lactis serves as a paradigm organism for the lactic acid bacteria (LAB).
Extensive research into the molecular biology, metabolism and physiology of several model …

A rapid and versatile tool for genomic engineering in Lactococcus lactis

T Guo, Y Xin, Y Zhang, X Gu, J Kong - Microbial Cell Factories, 2019 - Springer
Background Lactococcus lactis is one of the most extensively characterized lactic acid
bacteria, from physiological traits to industrial exploitation. Since last decade, L. lactis has …

Systems biology–A guide for understanding and developing improved strains of lactic acid bacteria

J Liu, SHJ Chan, J Chen, C Solem… - Frontiers in …, 2019 - frontiersin.org
Lactic Acid Bacteria (LAB) are extensively employed in the production of various fermented
foods, due to their safe status, ability to affect texture and flavor and finally due to the …

Metabolic engineering and synthetic biology employing Lactococcus lactis and Bacillus subtilis cell factories

AY van Tilburg, H Cao, SB van der Meulen… - Current opinion in …, 2019 - Elsevier
Highlights•Modifying metabolic fluxes in L. lactis and B. subtilis to obtain good production
hosts for food, pharma, and biotechnology.•Overview of synthetic biology tools for L. lactis …

Proteome constraints reveal targets for improving microbial fitness in nutrient‐rich environments

Y Chen, E van Pelt‐KleinJan, B van Olst… - Molecular Systems …, 2021 - embopress.org
Cells adapt to different conditions via gene expression that tunes metabolism for maximal
fitness. Constraints on cellular proteome may limit such expression strategies and introduce …