[HTML][HTML] Hydrogel-enabled, local administration and combinatorial delivery of immunotherapies for cancer treatment
Throughout the last decade, interventions to engineer the immune system called
immunotherapy have revolutionized the fields of oncology and autoimmune disease …
immunotherapy have revolutionized the fields of oncology and autoimmune disease …
Hydrogel drug delivery systems for minimally invasive local immunotherapy of cancer
AS Mikhail, R Morhard, M Mauda-Havakuk… - Advanced Drug Delivery …, 2023 - Elsevier
Although systemic immunotherapy has achieved durable responses and improved survival
for certain patients and cancer types, low response rates and immune system-related …
for certain patients and cancer types, low response rates and immune system-related …
A bright future: advanced nanotechnology-assisted microwave therapy
Y Du, J Zhou, F He, P Zang, H Gong, C Liu, P Yang - Nano Today, 2023 - Elsevier
Microwave has a promising therapeutic future due to its excellent minimally invasive, tissue
penetrating and organ specificity. Microwave-triggered therapeutic technology has received …
penetrating and organ specificity. Microwave-triggered therapeutic technology has received …
Janus silica nanoparticle-based tumor microenvironment modulator for restoring tumor sensitivity to programmed cell death ligand 1 immune checkpoint blockade …
X Lin, F Li, J Guan, X Wang, C Yao, Y Zeng, X Liu - ACS nano, 2023 - ACS Publications
An immunosuppressive tumor microenvironment (TME) with inadequate and exhausted
tumor-infiltrating cytotoxic lymphocytes and abundant cellular immunosuppressors is the …
tumor-infiltrating cytotoxic lymphocytes and abundant cellular immunosuppressors is the …
Metal‐cyclic dinucleotide nanomodulator‐stimulated STING signaling for strengthened radioimmunotherapy of large tumor
D Wang, T Nie, C Huang, Z Chen, X Ma, W Fang… - Small, 2022 - Wiley Online Library
Combined treatment of immunotherapy and radiotherapy shows promising therapeutic
effects for the regression of a variety of cancers. However, even multi‐modality therapies …
effects for the regression of a variety of cancers. However, even multi‐modality therapies …
A Booster for Radiofrequency Ablation: Advanced Adjuvant Therapy via In Situ Nanovaccine Synergized with Anti-programmed Death Ligand 1 Immunotherapy for …
Z Tian, Q Hu, Z Sun, N Wang, H He, Z Tang, W Chen - Acs Nano, 2023 - ACS Publications
Radiofrequency ablation (RFA) is one of the most common minimally invasive techniques for
treating hepatocellular carcinoma (HCC), which could destroy tumors through hyperthermia …
treating hepatocellular carcinoma (HCC), which could destroy tumors through hyperthermia …
Intelligent delivery system targeting PD-1/PD-L1 pathway for cancer immunotherapy
N Liu, R Zhang, Q Shi, H Jiang, Q Zhou - Bioorganic Chemistry, 2023 - Elsevier
The drugs targeting the PD-1/PD-L1 pathway have gained abundant clinical applications for
cancer immunotherapy. However, only a part of patients benefit from such immunotherapy …
cancer immunotherapy. However, only a part of patients benefit from such immunotherapy …
Programmed Upregulation of HSP70 by Metal‐Organic Frameworks Nanoamplifier for Enhanced Microwave Thermal‐Immunotherapy
W Guo, M Niu, Z Chen, Q Wu, L Tan… - Advanced …, 2022 - Wiley Online Library
Thermotherapy can directly kill tumor cells whilst being accompanied by immune‐enhancing
effects. However, this immune‐enhancing effect suffers from insufficient expression of …
effects. However, this immune‐enhancing effect suffers from insufficient expression of …
Prepared MW‐Immunosensitizers Precisely Release NO to Downregulate HIF‐1α Expression and Enhance Immunogenic Cell Death
W Guo, Z Chen, Q Wu, L Tan, X Ren, C Fu, F Cao… - Small, 2024 - Wiley Online Library
Microwave thermotherapy (MWTT) has limited its application in the clinic due to its high rate
of metastasis and recurrence after treatment. Nitric oxide (NO) is a gaseous molecule that …
of metastasis and recurrence after treatment. Nitric oxide (NO) is a gaseous molecule that …
A bio-responsive, cargo-catchable gel for postsurgical tumor treatment via ICD-based immunotherapy
Q Chen, S Zhou, Y Ding, D Chen, NS Dahiru… - Journal of Controlled …, 2022 - Elsevier
Tumor recurrence and metastasis after surgery remain challenges for tumor treatment.
Strategy that can promote the immunogenicity, activate adaptative immune response and …
Strategy that can promote the immunogenicity, activate adaptative immune response and …