[HTML][HTML] Gut–skin axis: current knowledge of the interrelationship between microbial dysbiosis and skin conditions

B De Pessemier, L Grine, M Debaere, A Maes… - Microorganisms, 2021 - mdpi.com
The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …

[HTML][HTML] Neutrophil extracellular traps (NETs) take the central stage in driving autoimmune responses

E Fousert, R Toes, J Desai - Cells, 2020 - mdpi.com
Following fifteen years of research, neutrophil extracellular traps (NETs) are widely reported
in a large range of inflammatory infectious and non-infectious diseases. Cumulating …

[HTML][HTML] Psoriatic arthritis: pathogenesis and targeted therapies

AB Azuaga, J Ramírez, JD Cañete - International journal of molecular …, 2023 - mdpi.com
Psoriatic arthritis (PsA), a heterogeneous chronic inflammatory immune-mediated disease
characterized by musculoskeletal inflammation (arthritis, enthesitis, spondylitis, and …

[HTML][HTML] Adaptive and innate immunity in psoriasis and other inflammatory disorders

MP Schön - Frontiers in immunology, 2019 - frontiersin.org
Over the past three decades, a considerable body of evidence has highlighted T cells as
pivotal culprits in the pathogenesis of psoriasis. This includes the association of psoriasis …

[HTML][HTML] Immunomodulatory role of the antimicrobial LL-37 peptide in autoimmune diseases and viral infections

B Pahar, S Madonna, A Das, C Albanesi, G Girolomoni - Vaccines, 2020 - mdpi.com
Antimicrobial peptides (AMPs) are produced by neutrophils, monocytes, and macrophages,
as well as epithelial cells, and are an essential component of innate immunity system …

[HTML][HTML] Psoriasis and antimicrobial peptides

T Takahashi, K Yamasaki - International journal of molecular sciences, 2020 - mdpi.com
Psoriasis is a systemic inflammatory disease caused by crosstalk between various cells
such as T cells, neutrophils, dendritic cells, and keratinocytes. Antimicrobial peptides (AMPs) …

[HTML][HTML] The IL-17/IL-23 axis and its genetic contribution to psoriatic arthritis

M Vecellio, VX Hake, C Davidson, MC Carena… - Frontiers in …, 2021 - frontiersin.org
Psoriatic arthritis (PsA) is a chronic inflammatory disease belonging to the family of
spondyloarthropathies (SpA). PsA commonly aggravates psoriasis of the skin and frequently …

[HTML][HTML] The molecular pathophysiology of psoriatic arthritis—the complex interplay between genetic predisposition, epigenetics factors, and the microbiome

AL Carvalho, CM Hedrich - Frontiers in molecular biosciences, 2021 - frontiersin.org
Psoriasis is a symmetric autoimmune/inflammatory disease that primarily affects the skin. In
a significant proportion of cases, it is accompanied by arthritis that can affect any joint, the …

Current knowledge on autoantigens and autoantibodies in psoriasis

LL Ten Bergen, A Petrovic… - … Journal of Immunology, 2020 - Wiley Online Library
In the past decades, clinical and experimental evidence has demonstrated that psoriasis is
an immune‐mediated inflammatory disease of the skin that occurs in genetically susceptible …

[HTML][HTML] The dual role of antimicrobial peptides in autoimmunity

W Liang, J Diana - Frontiers in immunology, 2020 - frontiersin.org
Autoimmune diseases (AiDs) are characterized by the destruction of host tissues by the host
immune system. The etiology of AiDs is complex, with the implication of multiple genetic …