Absorption enhancement of peach kernel oil on hydroxysafflor yellow A in safflower extracts and its mechanisms

T Ye, D Tang, C Tao, X Chen, X Wang, Y Xie - Food Chemistry, 2024 - Elsevier
Carthamus tinctorius L.(Safflower) is extensively used as a functional food and herbal
medicine, with its application closely associated with hydroxysafflor yellow A (HSYA) …

Osmotic Pressure and Its Biological Implications

S Zheng, Y Li, Y Shao, L Li, F Song - International Journal of Molecular …, 2024 - mdpi.com
Gaining insight into osmotic pressure and its biological implications is pivotal for revealing
mechanisms underlying numerous fundamental biological processes across scales and will …

In or out of the groove? Mechanisms of lipid scrambling by TMEM16 proteins

Z Feng, E Di Zanni, O Alvarenga, S Chakraborty… - Cell Calcium, 2024 - Elsevier
Phospholipid scramblases mediate the rapid movement of lipids between membrane
leaflets, a key step in establishing and maintaining membrane homeostasis of the …

Annexin A5 inhibits endothelial inflammation induced by lipopolysaccharide-activated platelets and microvesicles via phosphatidylserine binding

BJ Tschirhart, X Lu, J Gomes, A Chandrabalan, G Bell… - Pharmaceuticals, 2023 - mdpi.com
Sepsis is caused by a dysregulated immune response to infection and is a leading cause of
mortality globally. To date, no specific therapeutics are available to treat the underlying …

Phospholipid Complex Formulation Technology for Improved Drug Delivery in Oncological Settings: a Comprehensive Review

J Patil, DM Pawde, S Bhattacharya, S Srivastava - AAPS PharmSciTech, 2024 - Springer
Addressing poor solubility and permeability issues associated with synthetic drugs and
naturally occurring active compounds is crucial for improving bioavailability. This review …

Mendelian Randomization Analysis Identifies Causal Associations Between Serum Lipidomic Profile, Amino Acid Biomarkers and Sepsis

Z Zhu, J Ma, D Ji, Q Li, X Diao, J Bao - Heliyon, 2024 - cell.com
Background Sepsis is a life-threatening condition marked by a severe systemic response to
infection, leading to widespread inflammation, cellular signaling disruption, and metabolic …

[HTML][HTML] LC-MS-based untargeted metabolomics reveals the mechanism underlying prostate damage in a type 2 diabetes mouse model

R Qi, Y Pei, M Liu, Y Zhou, B Guan, X Zhang, Z Li… - Reproductive …, 2023 - Elsevier
Type 2 diabetes mellitus (T2DM) can cause prostate damage and affect male reproductive
function, but the underlying mechanisms are not completely understood. In this study, we …

Transient pores in hemifusion diaphragms

R Spencer, Y Smirnova, A Soleimani, M Müller - Biophysical Journal, 2024 - cell.com
Exchange of material across two membranes, as in the case of synaptic neurotransmitter
release from a vesicle, involves the formation and poration of a hemifusion diaphragm (HD) …

Interplay between cortical adhesion and membrane bending regulates microparticle formation

A Mahapatra, SA Malingen, P Rangamani - bioRxiv, 2024 - biorxiv.org
The formation of blebs and microparticle formation requires the bending of the plasma
membrane away from the cytosol. There are multiple factors that control the formation of the …

Mechanism of Nanoparticle Toxicity

PO Isibor, AS Sunday, AB Buba… - … : Combatting the Minute …, 2024 - Springer
Nanoparticles (NPs), materials less than 100 nm in size, are being utilised in diverse
biomedical, commercial, and industrial applications due to their unique physicochemical …