[HTML][HTML] Exosome–Autophagy Crosstalk in Enveloped Virus Infection

Y Wang, L Ren, H Bai, Q Jin, L Zhang - International journal of molecular …, 2023 - mdpi.com
Exosomes, which are extracellular vesicles (EVs) predominantly present in bodily fluids,
participate in various physiological processes. Autophagy, an intracellular degradation …

[HTML][HTML] The antimicrobial properties of cannabis and cannabis-derived compounds and relevance to CB2-targeted neurodegenerative therapeutics

HJ Hong, L Sloan, D Saxena, DA Scott - Biomedicines, 2022 - mdpi.com
Cannabinoid receptor 2 (CB2) is of interest as a much-needed target for the treatment or
prevention of several neurogenerative diseases. However, CB2 agonists, particularly …

[HTML][HTML] Effects of oral cannabinoids on systemic inflammation and viral reservoir markers in people with HIV on antiretroviral therapy: results of the CTN PT028 pilot …

RS Mboumba Bouassa, E Comeau, Y Alexandrova… - Cells, 2023 - mdpi.com
Chronic HIV infection is characterized by persistent inflammation despite antiretroviral
therapy (ART). Cannabinoids may help reduce systemic inflammation in people with HIV …

[HTML][HTML] In Vitro Antiproliferative Effect of Cannabis Extract PHEC-66 on Melanoma Cell Lines

A Bachari, N Nassar, S Telukutla, R Zomer… - Cells, 2023 - mdpi.com
Melanoma, an aggressive form of skin cancer, can be fatal if not diagnosed and treated
early. Melanoma is widely recognized to resist advanced cancer treatments, including …

[HTML][HTML] Anti-inflammatory effects of CBD in human microglial cell line infected with HIV-1

A Yndart Arias, N Kolishetti, A Vashist, L Madepalli… - Scientific Reports, 2023 - nature.com
Human immunodeficiency virus (HIV) infection is associated with a chronic inflammatory
stage and continuous activation of inflammasome pathway. We studied the anti …

[HTML][HTML] Safety and tolerability of oral cannabinoids in people living with HIV on long-term ART: a randomized, open-label, interventional pilot clinical trial (CTNPT 028)

RS Mboumba Bouassa, J Needham, D Nohynek… - Biomedicines, 2022 - mdpi.com
Background: With anti-inflammatory properties, cannabinoids may be a potential strategy to
reduce immune activation in people living with HIV (PLWH) but more information on their …

Extracellular vesicle isolation methods identify distinct HIV‐1 particles released from chronically infected T‐cells

SM Molnar, Y Kim, L Wieczorek… - Journal of …, 2024 - Wiley Online Library
The current study analyzed the intersecting biophysical, biochemical, and functional
properties of extracellular particles (EPs) with the human immunodeficiency virus type‐1 …

Broad-Spectrum antiviral effect of cannabidiol against enveloped and nonenveloped viruses

AB Marquez, J Vicente, E Castro, D Vota… - Cannabis and …, 2024 - liebertpub.com
Introduction: Cannabidiol (CBD), the main non-psychoactive cannabinoid of the Cannabis
sativa plant, is a powerful antioxidant compound that in recent years has increased interest …

[HTML][HTML] Evaluating the Metabolomic Profile and Anti-Pathogenic Properties of Cannabis Species

S Monyela, PN Kayoka, W Ngezimana, LE Nemadodzi - Metabolites, 2024 - mdpi.com
The Cannabis species is one of the potent ancient medicinal plants acclaimed for its
medicinal properties and recreational purposes. The plant parts are used and exploited all …

[HTML][HTML] Feasibility of a Randomized, Interventional Pilot Clinical Study of Oral Cannabinoids in People with HIV on Antiretroviral Therapy: CTNPT 028

RSM Bouassa, J Needham, D Nohynek… - Journal of …, 2024 - ncbi.nlm.nih.gov
Cannabis-based medicines (CBMs) could help reduce systemic inflammation in people with
HIV (PWH). In a prospective, randomized pilot study we enrolled participants from August …