Randomised controlled trials, including the National Lung Screening Trial (NLST) and the
NELSON trial, have shown reduced mortality with lung cancer screening with low-dose CT …

While lung cancer has been the leading cause of cancer-related deaths for many years in
the United States, incidence and mortality statistics–among other measures–vary widely …

Medical datasets are usually imbalanced, where negative cases severely outnumber
positive cases. Therefore, it is essential to deal with this data skew problem when training …

The present review is an update of the research and development efforts regarding the use
of molecular biomarkers in the lung cancer screening setting. The two main unmet clinical …

The TRIPOD (Transparent Reporting of a multivariable prediction model for Individual
Prognosis Or Diagnosis) Statement includes a 22-item checklist, which aims to improve the …

Lung cancer remains the leading cause of cancer related deaths worldwide. Lung cancer
screening using low-dose computed tomography (LDCT) has been shown to reduce lung …

Background Major issues in the implementation of screening for lung cancer by means of
low-dose computed tomography (CT) are the definition of a positive result and the …

Background The National Lung Screening Trial (NLST) used risk factors for lung cancer
(eg,≥ 30 pack-years of smoking and< 15 years since quitting) as selection criteria for lung …

Lung cancer continues to be a major global health problem; the disease is diagnosed in
more than 1.6 million new patients each year. However, significant progress is underway in …

Background In the National Lung Screening Trial (NLST), screening with low-dose
computed tomography (CT) resulted in a 20% reduction in lung-cancer mortality among …