Abstract Glucose‑6‑phosphate dehydrogenase (G6PD) is a cytoplasmic enzyme found in
human erythrocytes that provides reduced NADPH for cell metabolism. Glutathione …

Tumor associated macrophages (TAMs) have a crucial role in cancer progression,
metastasis and drug response. Piroxicam and sulindac sulfide are non-steroidal anti …

Abstract Prostate apoptosis response‐4 (Par‐4) tumor suppressor protein has gained
attention as a potential therapeutic target owing to its unique ability to selectively induce …

Due to the lack of markers (ER, PR, and HER-2/Neu) for the molecular-targeted therapies
triple-negative breast cancer (TNBC) is more challenging than other subtypes of breast …

Gliomas are the most common type of primary brain tumors and glioblastoma (GBM), the
most lethal of gliomas accounts for more than 60% of all brain tumors in adults. Despite the …

X chromosome inactivation is the epitome of epigenetic regulation and long non-coding
ribonucleic acid function. The differentiation status of cells has been ascribed to X …

Background: Peniciketal A (Pe-A), a spiroketal compound, shows potent anticancer activities
in human acute monocytic leukemia. However, the detailed mechanisms and potent targets …

Cancer continues to be the leading global cause of death, with challenges in early
diagnosis, drug resistance, non-specific drug targeting, and cancer recurrence and …

在肿瘤治疗中, 寻找选择性作用于肿瘤细胞的药物是人们所期待和向往的. 前列腺凋亡反应蛋白-
4 (prostate apoptosis response protein-4, Par-4) 作为肿瘤抑制因子, 能选择性诱导肿瘤细胞凋 …

: X chromosome inactivation is the epitome of epigenetic regulation and long
non-coding ribonucleic acid function. The differentiation status of cells has been ascribed to …