Osteoarthritis (OA) is the most common chronic disease of human joints. The basis of
pathologic changes involves all the tissues forming the joint; already, at an early stage, it has …

Osteoarthritis (OA) has traditionally been classified as a noninflammatory arthritis; however,
the dichotomy between inflammatory and degenerative arthritis is becoming less clear with …

Osteoarthritis (OA) is a debilitating degenerative joint disease particularly affecting
weightbearing joints within the body, principally the hips and knees. Current radiographic …

Osteoarthritis (OA) is highly prevalent and a leading cause of disability worldwide. Despite
the global burden of OA, diagnostic tests and treatments for the molecular or early …

Human osteoarthritis is a systemic musculoskeletal disorder involving activation of innate
and adaptive immune systems accompanied by inflammation exemplified by the elevated …

Meniscal injuries have posed a challenging problem for many years, especially considering
that historically the meniscus was considered to be a structure with no important role in the …

Spermidine has been known to inhibit the production of pro-inflammatory cytokines.
However, there are no reports about anti-inflammatory effects of spermidine on osteoarthritis …

Objective The aim of this systematic review was to analyze the evidence about the efficacy of
the several synovial fluid (SF) biomarkers proposed for knee osteoarthritis (OA), categorizing …

OBJECTIVE: Soluble mediators in synovial fluid (SF) are acknowledged as key players in
the pathophysiology of osteoarthritis (OA). However, a wide-spectrum screening of such …

Chemokines are pivotal players in instigation and perpetuation of synovitis through
leukocytes egress from the blood circulation into the inflamed articulation. Multitudinous …