Pancreatic ductal adenocarcinoma (PDAC) has one of the worst prognoses among all
malignancies. PI3K/AKT/mTOR signaling pathway, a main downstream effector of KRAS is …

Pancreatic cancer is an aggressive malignancy with increasing incidence and poor
prognosis due to its late diagnosis and intrinsic chemoresistance. Most pancreatic cancer …

Gemcitabine is a nucleoside analog that has been successfully used in the treatment of
multiple cancers. However, intrinsic or acquired resistance reduces the chemotherapeutic …

Cancer heterogeneity constitutes the major source of disease progression and therapy
failure. Tumors comprise functionally diverse subpopulations, with cancer stem cells (CSCs) …

Wnt/β‐catenin pathway is one of the main/frequent dysregulated pathways in several tumor
types, including colon cancer. Aberrant activation of this pathway is associated with cell …

Cancer metastasis to distant organs is initiated by tumor cells that disseminate from primary
heterogeneous tumors. The subsequent growth and survival of tumor metastases depend on …

ABSTRACT PI3K/AKT/mTOR signaling pathway is one of the key dysregulated pathways in
different tumor types, including colorectal cancer (CRC). Activation of this pathway is shown …

Cervical cancer is a common gynecological cancer and a leading cause of cancer‐related
death in women globally. There is a need for the identification of prognostic and predictive …

Non-small cell lung carcinoma (NSCLC) is the most common cancer globally.
Phytochemicals and small molecule inhibitors significantly prevent varying types of cancers …

Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive neoplasm, predicted
to become the second leading cause of cancer-related deaths before 2030. This dismal …