Progesterone actions and resistance in gynecological disorders

JA MacLean, K Hayashi - Cells, 2022 - mdpi.com
Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

Endometrial hyperplasia

KL Ring, AM Mills, SC Modesitt - Obstetrics & Gynecology, 2022 - journals.lww.com
The objectives of this Clinical Expert Series on endometrial hyperplasia are to review the
etiology and risk factors, histologic classification and subtypes, malignant progression risks …

USA endometrial cancer projections to 2030: should we be concerned?

MA Sheikh, AD Althouse, KE Freese, S Soisson… - Future …, 2014 - Taylor & Francis
Aim: As the incidence of endometrial cancer (EC) increased considerably since 2007, this
study aimed to project the burden of EC to the year 2030. Methods: Multivariate linear …

Diagnosis and management of endometrial hyperplasia

AJ Armstrong, WW Hurd, S Elguero, NM Barker… - Journal of minimally …, 2012 - Elsevier
Endometrial hyperplasia (EH), with or without atypia, is a common gynecologic diagnosis
and a known precursor of endometrial carcinoma, the most common gynecologic …

The impact of obesity and bariatric surgery on circulating and tissue biomarkers of endometrial cancer risk

ML MacKintosh, AE Derbyshire… - … journal of cancer, 2019 - Wiley Online Library
Obesity is the strongest risk factor for endometrial cancer (EC). To inform targeted screening
and prevention strategies, we assessed the impact of obesity and subsequent bariatric …

Altered gene expression profiling in endometrium: evidence for progesterone resistance

L Aghajanova, MC Velarde… - Seminars in reproductive …, 2010 - thieme-connect.com
Progesterone plays an important role in regulating multiple events in the uterus. It controls
endometrial proliferation and differentiation, which are important for uterine function …

Asymptomatic endometrial thickening

W Wolfman, N Leyland, M Heywood, SS Singh… - Journal of Obstetrics and …, 2010 - Elsevier
Objective To formulate clinical recommendations for the assessment of endometrial
thickening when it is found on ultrasound in a postmenopausal patient without bleeding …

Executive summary of the uterine cancer evidence review conference

D Chelmow, R Brooks, A Cavens… - Obstetrics & …, 2022 - journals.lww.com
David Chelmow, MD, Rebecca Brooks, MD, Arjeme Cavens, MD, Kathryn Huber-Keener,
MD, PhD, Dana M. Scott, MD, Sangini S. Sheth, MD, MPH, Sara Whetstone, MD, MHS, Brett …

Endometrial cancer risk prediction according to indication of diagnostic hysteroscopy in post-menopausal women

C Saccardi, A Vitagliano, M Marchetti, A Lo Turco… - Diagnostics, 2020 - mdpi.com
We conducted a prospective observational study investigating the clinical relevance of
endometrial thickness (ET) and abnormal uterine bleeding (AUB) on endometrial cancer …

New light on endometrial thickness as a risk factor of cancer: what do clinicians need to know?

C Saccardi, G Spagnol, G Bonaldo… - Cancer Management …, 2022 - Taylor & Francis
Transvaginal ultrasound (TVUS) represents an accurate and noninvasive technique to
investigate endometrial thickness (ET) in the early diagnosis of endometrial cancer (EC). In …