[HTML][HTML] The TNF-α rs361525 and IFN-γ rs2430561 polymorphisms are associated with liver cirrhosis risk: a comprehensive meta-analysis

M Zheng, J Li, W Fang, L Luo, R Ding, H Zeng… - Frontiers in …, 2023 - frontiersin.org
Background Inflammation serves as an essential driver of liver cirrhosis (LC) incidence.
Accordingly, a meta-analysis was carried out to explore the association between specific …

[HTML][HTML] Gene polymorphisms of inflammatory factors in liver cirrhosis

S Xiao, X Pan, X Huang, Y Liu, SW Wen, A Liu - Frontiers in Genetics, 2023 - frontiersin.org
Introduction: Studies on the association between gene polymorphisms of various
inflammatory factors and liver cirrhosis have been inconsistent. The purpose of this study …

[HTML][HTML] IL-6 and IL-10 gene polymorphisms and cirrhosis of liver risk from a comprehensive analysis

M Zheng, W Fang, M Yu, R Ding, H Zeng… - BMC Endocrine …, 2021 - Springer
Background Different inflammatory and immune cytokines play a key role in the
development of cirrhosis of liver (CL). To investigate the association between interleukin-6 …

High expression of FAM13A was associated with increasing the liver cirrhosis risk

Y Zhang, S Wang, C Wang, J Xiao… - Molecular Genetics & …, 2019 - Wiley Online Library
Aim Liver cirrhosis is a consequence of chronic liver disease, and it may be caused by
multiple influences of both genetic and environmental factors. Family with sequence …

The Impact of Interferon-γ (IFN-γ) and IFN-γ-Inducible Protein 10 (IP-10) Genes' Polymorphism on Risk of Hepatitis C Virus–Related Liver Cirrhosis

RM Talaat, S Elsharnoby, MS Abdelkhalek… - Immunological …, 2022 - Taylor & Francis
Background Today there is increasing evidence concerning the association between
individual genetic polymorphisms within proinflammatory cytokines and chronic hepatitis C …

[HTML][HTML] TNFA -308G>A and IL10 -1082A>G polymorphisms seem to be predictive biomarkers of chronic HCV infection

AM Santiago, E da Silva Graça Amoras… - BMC Infectious …, 2021 - Springer
Background Genetic changes may induce dysregulated cytokine production and affect the
progression of the chronic disease caused by the hepacivirus C (HCV) because the balance …

[HTML][HTML] The TGFB1-509C/T polymorphism and elevated TGF-β1 levels are associated with chronic hepatitis C and cirrhosis

WB de Brito, MAF Queiroz, ESG Amoras, SS Lima… - Immunobiology, 2020 - Elsevier
The IFN-γ and TGF-β1 cytokines perform antagonistic activities in the immune response, and
polymorphisms in these genes may induce changes in their plasma levels and influence the …

[HTML][HTML] Genetic polymorphisms in ataxin-3 and liver cirrhosis risk related to aflatoxin B1

XZ Wang, XY Huang, JG Yao, C Wang, Q Xia… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Background Altered expression of ataxin-3 (AT3) can modify DNA repair capacity and is
observed in human diseases. The genetic polymorphisms of this gene in aflatoxin B1 (AFB1) …

[HTML][HTML] Эффект полиморфизма генов IL10 (rs1800872) и CXCL10 (rs4386624, rs4256246) в развитии инфекционных заболеваний вирусной и бактериальной …

ИА Гончарова, ЕЮ Брагина… - Научные …, 2019 - cyberleninka.ru
Актуальность: Контакт человека с патогенными микроорганизмами является
необходимым, но недостаточным условием для развития болезни. Иммунный ответ на …

Elevated serum IP-10/CXCL10 levels are associated with sarcopenia development, a prognostic factor, in patients with primary hepatocellular carcinoma

H Takada, K Yamashita, L Osawa, Y Komiyama… - 2023 - researchsquare.com
Sarcopenia is a prognostic factor in patients with hepatocellular carcinoma (HCC). However,
the mechanism underlying sarcopenia development in patients with HCC remains unclear …