Endogenous microRNA sponges: evidence and controversy
DW Thomson, ME Dinger - Nature Reviews Genetics, 2016 - nature.com
The competitive endogenous RNA (ceRNA) hypothesis proposes that transcripts with
shared microRNA (miRNA) binding sites compete for post-transcriptional control. This …
shared microRNA (miRNA) binding sites compete for post-transcriptional control. This …
[HTML][HTML] Viruses and miRNAs: more friends than foes
P Bruscella, S Bottini, C Baudesson… - Frontiers in …, 2017 - frontiersin.org
There is evidence that eukaryotic miRNAs (hereafter called host miRNAs) play a role in the
replication and propagation of viruses. Expression or targeting of host miRNAs can be …
replication and propagation of viruses. Expression or targeting of host miRNAs can be …
SARS-CoV-2 expresses a microRNA-like small RNA able to selectively repress host genes
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease (COVID-19), continues to be a pressing health concern. In this study …
coronavirus disease (COVID-19), continues to be a pressing health concern. In this study …
Understanding microRNA-mediated gene regulatory networks through mathematical modelling
The discovery of microRNAs (miRNAs) has added a new player to the regulation of gene
expression. With the increasing number of molecular species involved in gene regulatory …
expression. With the increasing number of molecular species involved in gene regulatory …
[HTML][HTML] Dysregulated expression of long noncoding RNAs in gynecologic cancers
ES Hosseini, M Meryet-Figuiere, H Sabzalipoor… - Molecular cancer, 2017 - Springer
Cancers of the female reproductive system include ovarian, uterine, vaginal, cervical and
vulvar cancers, which are termed gynecologic cancer. The emergence of long noncoding …
vulvar cancers, which are termed gynecologic cancer. The emergence of long noncoding …
[HTML][HTML] Target RNAs strike back on microRNAs
F Fuchs Wightman, LE Giono, JP Fededa… - Frontiers in …, 2018 - frontiersin.org
MicroRNAs are extensively studied regulatory non-coding small RNAs that silence animal
genes throughout most biological processes, typically doing so by binding to partially …
genes throughout most biological processes, typically doing so by binding to partially …
Hepatitis B virus-human chimeric transcript HBx-LINE1 promotes hepatic injury via sequestering cellular microRNA-122
HW Liang, N Wang, Y Wang, F Wang, Z Fu, X Yan… - Journal of …, 2016 - Elsevier
Background & Aims Chronic hepatitis B virus (HBV) carriers have a high risk to develop
hepatocellular carcinoma (HCC) but the underlying mechanism remains unclear. Recent …
hepatocellular carcinoma (HCC) but the underlying mechanism remains unclear. Recent …
[HTML][HTML] The potential use of microRNAs as a therapeutic strategy for SARS-CoV-2 infection
J Hu, J Stojanović, S Yasamineh, P Yasamineh… - Archives of …, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). To date, there is no effective therapeutic approach …
syndrome coronavirus 2 (SARS-CoV-2). To date, there is no effective therapeutic approach …
[HTML][HTML] Non-coding RNAs and endometrial cancer
C Vallone, G Rigon, C Gulia, A Baffa, R Votino… - Genes, 2018 - mdpi.com
Non-coding RNAs (ncRNAs) are involved in the regulation of cell metabolism and neoplastic
transformation. Recent studies have tried to clarify the significance of these information …
transformation. Recent studies have tried to clarify the significance of these information …
[HTML][HTML] Broad-spectrum inhibition of respiratory virus infection by microRNA mimics targeting p38 MAPK signaling
JL McCaskill, S Ressel, A Alber, J Redford… - … Therapy-Nucleic Acids, 2017 - cell.com
The majority of antiviral therapeutics target conserved viral proteins, however, this approach
confers selective pressure on the virus and increases the probability of antiviral drug …
confers selective pressure on the virus and increases the probability of antiviral drug …