The fields of application of functional proteomics are not limited to the study of protein–
protein interactions; they also extend to those involving protein complexes that bind DNA or …

The Y Box binding protein 1 (YB-1) is a member of the highly conserved Cold Shock Domain
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …

Simple Summary Proteins are composed of compact domains, often of known three-
dimensional structure, and natively unstructured polypeptide regions. The abundant cold …

Purpose: Cisplatin-based chemotherapy effectively improves the distant-metastasis control
in nasopharyngeal carcinoma (NPC), but approximately 30% of patients develop treatment …

In heterogeneous head and neck cancer (HNC), subtype-specific treatment regimens are
currently missing. An integrated analysis of patient HNC subtypes using single-cell …

Aging is accompanied by many physiological changes. These changes can progressively
lead to many types of cardiovascular diseases. During this process blood vessels lose their …

In the absence of the scanning ribosomes that unwind mRNA coding sequences and 5′
UTRs, mRNAs are likely to form secondary structures and intermolecular bridges …

T-LAK-originated protein kinase (TOPK), a dual specificity serine/threonine kinase, is up-
regulated and related to poor prognosis in many types of cancers. Y-box binding protein 1 …

Diabetic cardiomyopathy (DCM) is a major complication of diabetes, but its underlying
mechanisms still remain unclear. The multifunctional protein Y-box binding protein-1 (YB-1) …

Simple Summary Signals that determine cell survival or death are essential for maintaining
tissue homeostasis. Cell death promotes the removal of unwanted cells; however, a failure …