Versatile spider venom peptides and their medical and agricultural applications

NJ Saez, V Herzig - Toxicon, 2019 - Elsevier
Spiders have been evolving complex and diverse repertoires of peptides in their venoms
with vast pharmacological activities for more than 300 million years. Spiders use their …

Phoneutria nigriventer venom: A pharmacological treasure

S Peigneur, ME de Lima, J Tytgat - Toxicon, 2018 - Elsevier
In millions of years, spiders have optimized their venoms in order to assure successful prey
capture and defence against predators. Spider venoms have become unique cocktails of …

[HTML][HTML] Spider venom peptides as potential drug candidates due to their anticancer and antinociceptive activities

T Wu, M Wang, W Wu, Q Luo, L Jiang, H Tao… - Journal of Venomous …, 2019 - SciELO Brasil
Spider venoms are known to contain proteins and polypeptides that perform various
functions including antimicrobial, neurotoxic, analgesic, cytotoxic, necrotic, and …

Insight into the possible mechanism (s) involved in the antinociceptive and antineuropathic activity of Descurainia sophia L. Webb ex Prantl essential oil

DZ Abed, S Jabbari, ZA Zakaria… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Descurainia sophia (L.)(Brassicaceae), popularly known
as “Khaksheer”, is a native species widely distributed in Iran. The seeds and essential oil …

[HTML][HTML] Biomedical applications of synthetic peptides derived from venom of animal origin: A systematic review

JL Díaz-Gómez, I Martín-Estal, E Rivera-Aboytes… - Biomedicine & …, 2024 - Elsevier
Abstract Development of therapeutic agents that have fewer adverse effects and have higher
efficacy for diseases, such as cancer, metabolic disorders, neurological diseases, infections …

Pain modulatory properties of Phoneutria nigriventer crude venom and derived peptides: a double-edged sword

PSS Lauria, CF Villarreal, LL Casais-e-Silva - Toxicon, 2020 - Elsevier
Phoneutria nigriventer venom (PNV) is a complex mixture of toxins exerting multiple
pharmacological effects that ultimately result in severe local pain at the site of the bite. It has …

[HTML][HTML] Pnpp-19 peptide as a novel drug candidate for topical glaucoma therapy through nitric oxide release

CN da Silva, LFN Dourado, ME de Lima… - … Vision Science & …, 2020 - iovs.arvojournals.org
Purpose: Evaluation of PnPP-19 safety and efficacy in reducing the intraocular pressure
(IOP) of animals with healthy (normotensive) and ocular hypertensive eyes. PnPP-19 is a …

Nitrate reductase-dependent nitric oxide plays a key role on MeJA-induced ganoderic acid biosynthesis in Ganoderma lucidum

L Shi, S Yue, T Gao, J Zhu, A Ren, H Yu… - Applied Microbiology …, 2020 - Springer
Ganoderma lucidum, which contains numerous biologically active compounds, is known
worldwide as a medicinal basidiomycete. Because of its application for the prevention and …

[HTML][HTML] Unveiling the Pain Relief Potential: Harnessing Analgesic Peptides from Animal Venoms

AFM Pereira, JS Cavalcante, DG Angstmam… - Pharmaceutics, 2023 - mdpi.com
The concept of pain encompasses a complex interplay of sensory and emotional
experiences associated with actual or potential tissue damage. Accurately describing and …

The oral administration of Lotus corniculatus L. attenuates acute and chronic pain models in male rats

S Jabbari, ZA Zakaria, D Ahmadimoghaddam… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Lotus corniculatus L.(Fabaceae) traditionally used in
Persian folk medicine to heal peritoneal inflammation and back pain. Aim of the study To …