Defective mitophagy in Alzheimer's disease

JA Pradeepkiran, PH Reddy - Ageing Research Reviews, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive, mental illness without cure. Several years of
intense research on postmortem AD brains, cell and mouse models of AD have revealed …

Role and mechanisms of mitophagy in liver diseases

X Ma, T McKeen, J Zhang, WX Ding - Cells, 2020 - mdpi.com
The mitochondrion is an organelle that plays a vital role in the regulation of hepatic cellular
redox, lipid metabolism, and cell death. Mitochondrial dysfunction is associated with both …

[HTML][HTML] Mitophagy and mitochondrial dynamics in type 2 diabetes mellitus treatment

Z Shan, WH Fa, CR Tian, CS Yuan, N Jie - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
The prevalence of type 2 diabetes is associated with inflammatory bowels diseases,
nonalcoholic steatohepatitis and even a spectrum of cancer such as colon cancer and liver …

Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis

T Liu, Q Yang, X Zhang, R Qin, W Shan, H Zhang… - Life Sciences, 2020 - Elsevier
Emerging evidence implicates accelerated renal tubular epithelial cell (RTEC) senescence
in renal fibrosis progression. Mitophagy protects against kidney injury. However, the …

[HTML][HTML] Subcellular damages of Colletotrichum asianum and inhibition of mango anthracnose by dielectric barrier discharge plasma

Y Wu, JH Cheng, DW Sun - Food Chemistry, 2022 - Elsevier
Colletotrichum asianum (C. asianum) is a new pathogenic fungus that causes mango
anthracnose. Cold plasma is a novel non-thermal decontamination technology, which has …

Flavonoids and mitochondria: activation of cytoprotective pathways?

A Kicinska, W Jarmuszkiewicz - Molecules, 2020 - mdpi.com
A large number of diverse mechanisms that lead to cytoprotection have been described to
date. Perhaps, not surprisingly, the role of mitochondria in these phenomena is notable. In …

Polyphenols as caloric restriction mimetics regulating mitochondrial biogenesis and mitophagy

S Davinelli, D De Stefani, I De Vivo… - Trends in Endocrinology & …, 2020 - cell.com
The tight coordination between mitochondrial biogenesis and mitophagy can be
dysregulated during aging, critically influencing whole-body metabolism, health, and …

Targeting heme oxygenase-1 by quercetin ameliorates alcohol-induced acute liver injury via inhibiting NLRP3 inflammasome activation

S Liu, L Tian, G Chai, B Wen, B Wang - Food & function, 2018 - pubs.rsc.org
Alcoholic hepatitis (AH) is characterized by inflammation and necrosis of liver tissue caused
by excessive alcohol consumption and it even causes organ failure sometimes, in which …

Pathogenesis of alcohol-associated liver disease

NA Osna, K Rasineni, M Ganesan… - Journal of Clinical and …, 2022 - Elsevier
Excessive alcohol consumption is a global healthcare problem with enormous social,
economic, and clinical consequences. While chronic, heavy alcohol consumption causes …

Dietary polyphenols and obesity: A review of polyphenol effects on lipid and glucose metabolism, mitochondrial homeostasis, and starch digestibility and absorption

CS Dzah, D Asante-Donyinah, E Letsyo… - Plant Foods for Human …, 2023 - Springer
Obesity is a major global public health concern, limiting socio-economic development and
human productivity. As studies focus on finding sustainable solutions to this challenge …