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Pertussis, or whooping cough, is a highly contagious, acute respiratory disease of humans
that is caused by the Gram-negative bacterial pathogen Bordetella pertussis. In the face of …

Pertussis is still among the principal causes of death worldwide, and its incidence is
increasing even in countries with high vaccine coverage. Although all age groups are …

Whooping cough is considered a childhood disease, although there is growing evidence
that children are infected by adult carriers. Additionally, increasing numbers of vaccinated …

Worldwide, the prevalence of noncommunicable chronic diseases is increasing. The use of
vaccines to induce autoantibodies that neutralize disease-related proteins offers a means to …

Bordetella pertussis and Bordetella bronchiseptica belong to the genus Bordetella, which
comprises 14 other species. B. pertussis is responsible for whooping cough in humans, a …

Ricin, a highly potent toxin produced by castor beans, is classified by the Centers for
Disease Control and Prevention as a level B biothreat because it is easily produced, readily …

Pertussis toxin (PT) is one of the major virulence factors of Bordetella pertussis and the
primary component of all pertussis vaccines available to date. Because of its various …

An international meeting on Bordetella pertussis assay standardization and harmonization
was held at the Centers for Disease Control and Prevention (CDC), Atlanta, GA, 19–20 July …

Immunogenicity data for the pertussis components of the French diphtheria-tetanus-two
component acellular pertussis vaccine (DTaP2Fr) obtained after primary series of …