Inflammation and prostate cancer: the role of interleukin 6 (IL‐6)

DP Nguyen, J Li, AK Tewari - BJU international, 2014 - Wiley Online Library
Environmental and genetic aspects are reflected in the development of prostate cancer. In
this context, there is growing evidence that chronic inflammation is involved in the regulation …

Recent insights into NF‐κ B signalling pathways and the link between inflammation and prostate cancer

DP Nguyen, J Li, SS Yadav, AK Tewari - BJU international, 2014 - Wiley Online Library
Inflammation is involved in regulation of cellular events in prostate carcinogenesis through
control of the tumour micro‐environment. A variety of bone marrow‐derived cells, including …

Tissue injury and hypoxia promote malignant progression of prostate cancer by inducing CXCL13 expression in tumor myofibroblasts

M Ammirante, S Shalapour, Y Kang… - Proceedings of the …, 2014 - National Acad Sciences
Prostate cancer (PC) is a slowly progressing malignancy that often responds to androgen
ablation or chemotherapy by becoming more aggressive, acquiring a neuroendocrine …

Prognostic role of NLR in urinary cancers: a meta-analysis

Y Wei, YZ Jiang, WH Qian - PloS one, 2014 - journals.plos.org
Background Recently, many studies explored the role of inflammation parameters such as
neutrophil-to-lymphocyte ratio (NLR) in the prognosis of urinary cancers, but the results were …

Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases

AL Hardaway, MK Herroon, E Rajagurubandara… - Cancer and Metastasis …, 2014 - Springer
Adipocytes are important but underappreciated components of bone marrow
microenvironment, and their numbers greatly increase with age, obesity, and associated …

Research trends and regulation of CCL5 in prostate cancer

R Huang, L Guo, M Gao, J Li, S Xiang - OncoTargets and therapy, 2021 - Taylor & Francis
Prostate cancer (PCa) is considered as the most common cancer of urologic neoplasms,
and its development and prognosis are associated with many factors. Chemokine receptor …

Pretreatment neutrophil-to-lymphocyte ratio in metastatic castration-resistant prostate cancer patients treated with ketoconazole: association with outcome and …

D Keizman, M Gottfried, M Ish-Shalom… - The …, 2012 - academic.oup.com
Background. The neutrophil-to-lymphocyte ratio (NLR), an inflammation marker, is
prognostic in several cancers. We assessed the association between the pretreatment NLR …

Distinct phenotypes of human prostate cancer cells associate with different adaptation to hypoxia and pro-inflammatory gene expression

L Ravenna, L Principessa, A Verdina, L Salvatori… - PLoS …, 2014 - journals.plos.org
Hypoxia and inflammation are strictly interconnected both concurring to prostate cancer
progression. Numerous reports highlight the role of tumor cells in the synthesis of pro …

Hematogenous dissemination of mesenchymal stem cells from endometriosis

F Li, MH Alderman III, A Tal, R Mamillapalli… - Stem Cells, 2018 - academic.oup.com
Endometriosis is ectopic growth of endometrial tissue traditionally thought to arise through
retrograde menstruation. We aimed to determine if cells derived from endometriosis could …

Prognostic role of C-reactive protein in urological cancers: a meta-analysis

L Zhou, X Cai, Q Liu, ZY Jian, H Li, KJ Wang - Scientific reports, 2015 - nature.com
Growing evidence suggests serum C-reactive protein (CRP) can serve as a prognostic
marker in urological cancers. However, some studies yield contradictory results. Our …