Biologically active γ-lactams: synthesis and natural sources

J Caruano, GG Muccioli, R Robiette - Organic & biomolecular …, 2016 - pubs.rsc.org
The γ-lactam moiety is present in a large number of natural and non-natural biologically
active compounds. The range of biological activities covered by these compounds is very …

[HTML][HTML] Synthetic approaches towards alkaloids bearing α-tertiary amines

A Hager, N Vrielink, D Hager, J Lefranc… - Natural product …, 2016 - pubs.rsc.org
Covering: up to August 2015 Alkaloids account for some of the most beautiful and
biologically active natural products. Although they are usually classified along biosynthetic …

Nicotinic acetylcholine receptor agonists: a milestone for modern crop protection

P Jeschke, R Nauen, ME Beck - … Chemie International Edition, 2013 - Wiley Online Library
The destruction of crops by invertebrate pests is a major threat against a background of a
continuously rising demand in food supply for a growing world population. Therefore …

Palladium-Catalyzed Carbonylations: Application in Complex Natural Product Total Synthesis and Recent Developments

HS Sims, M Dai - The Journal of Organic Chemistry, 2023 - ACS Publications
Carbon monoxide is a cheap and abundant C1 building block that can be readily
incorporated into organic molecules to rapidly build structural complexity. In this Perspective …

Unified total synthesis of stemoamide-type alkaloids by chemoselective assembly of five-membered building blocks

M Yoritate, Y Takahashi, H Tajima… - Journal of the …, 2017 - ACS Publications
A unified total synthesis of stemoamide-type alkaloids is reported. Our synthetic approach
features the chemoselective convergent assembly of five-membered building blocks via …

Rhodium (II)‐Catalyzed Intramolecular Annulation of 1‐Sulfonyl‐1, 2, 3‐Triazoles with Pyrrole and Indole Rings: Facile Synthesis of N‐Bridgehead Azepine Skeletons

JM Yang, CZ Zhu, XY Tang… - Angewandte Chemie …, 2014 - Wiley Online Library
A convenient and efficient synthetic method has been developed to construct highly
functionalized N‐bridgehead azepine skeletons, which are of great importance in biological …

Lactam hydrogen bonds as control elements in enantioselective transition-metal-catalyzed and photochemical reactions

F Burg, T Bach - The Journal of Organic Chemistry, 2019 - ACS Publications
In the last two decades, hydrogen bonds have been established as useful interactions to
control the selectivity of various chemical transformations. In this Perspective, the …

Total synthesis of complex alkaloids by nucleophilic addition to amides

T Sato, M Yoritate, H Tajima, N Chida - Organic & biomolecular …, 2018 - pubs.rsc.org
Nucleophilic addition to amides has been recognized as a promising transformation for total
synthesis of complex alkaloids. Amides can accept two different organometallic reagents …

[HTML][HTML] Structural classification and biological activities of Stemona alkaloids

H Greger - Phytochemistry Reviews, 2019 - Springer
Stemona alkaloids represent a unique class of natural products exclusively known from the
three genera Stemona, Stichoneuron, and Croomia of the monocotyledonous family …

[HTML][HTML] Enantioselective construction of cis-hydroindole scaffolds via an asymmetric inverse-electron-demand Diels–Alder reaction: application to the formal total …

F Zhang, BT Ren, Y Zhou, Y Liu, X Feng - Chemical Science, 2022 - pubs.rsc.org
cis-Hydroindole scaffolds widely exist in a large number of natural products,
pharmaceuticals, and organocatalysts. Therefore, the development of efficient and …